When a particular mutagen identified by the Ames testis injected into mice, it causes the appearance of manytumors, showing that this substance is carcinogenic.When cells from these tumors are injected into othermice not exposed to the mutagen, almost all of the newmice develop tumors. However, when mice carryingmutagen-induced tumors are mated to unexposed mice,virtually all of the progeny are tumor free. Why can thetumor be transferred horizontally (by injecting cells)but not vertically (from one generation to the next)?

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Asked Mar 10, 2020
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When a particular mutagen identified by the Ames test
is injected into mice, it causes the appearance of many
tumors, showing that this substance is carcinogenic.
When cells from these tumors are injected into other
mice not exposed to the mutagen, almost all of the new
mice develop tumors. However, when mice carrying
mutagen-induced tumors are mated to unexposed mice,
virtually all of the progeny are tumor free. Why can the
tumor be transferred horizontally (by injecting cells)
but not vertically (from one generation to the next)?

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Expert Answer

Step 1

The process by which genes are transferred from one organism to another is known as gene transfer. There are two types of gene transfer. These are horizontal gene transfer and vertical g...

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