Which observation suggested to Sutherland the involvementof a second messenger in epinephrine’s effect on liver cells?(A) Enzymatic activity was proportional to the amount ofcalcium added to a cell-free extract.(B) Receptor studies indicated that epinephrine was a ligand.(C) Glycogen breakdown was observed only when epinephrinewas administered to intact cells.(D) Glycogen breakdown was observed only when epinephrineand glycogen phosphorylase were mixed.

Question

Which observation suggested to Sutherland the involvement
of a second messenger in epinephrine’s effect on liver cells?
(A) Enzymatic activity was proportional to the amount of
calcium added to a cell-free extract.
(B) Receptor studies indicated that epinephrine was a ligand.
(C) Glycogen breakdown was observed only when epinephrine
was administered to intact cells.
(D) Glycogen breakdown was observed only when epinephrine
and glycogen phosphorylase were mixed.

Expert Answer

Want to see the step-by-step answer?

Check out a sample Q&A here.

Want to see this answer and more?

Experts are waiting 24/7 to provide step-by-step solutions in as fast as 30 minutes!*

*Response times may vary by subject and question complexity. Median response time is 34 minutes for paid subscribers and may be longer for promotional offers.
Tagged in
Science
Biology

Animal Physiology

Related Biology Q&A

Find answers to questions asked by students like you.

Q: Answer the following biology question in detail: If some one consumes the artificial steroid then wh...

A: Artificial steroids are androgenic compounds that are structurally similar to the male reproductive ...

Q: What critical event occurs during the S phase of the eukaryoticcell cycle?a. Cells make a decision o...

A: The cell cycle is the series of events that take place in a cell leading to division and duplication...

Q: What is the difference between sister chromatids and homologous chromosomes?

A: Homologous chromosomes are those chromosomes that have the same set of genes but are not genetically...

Q: In a line of human cells grown in culture, a geneticist isolates a temperature-sensitive mutation at...

A: Histone acetyltransferase (HATs) are those enzymes that can acetylate the lysine amino acids on hist...

Q: The fatty acids that must be obtained from diet because they are important to man are used to produc...

A: The breakdown of fats stored in the body yields fatty acids. Fatty acids are utilized to meet energy...

Q: If you conducted an acid-fast stain on a sputum sample from a person with tuberculosis, what would y...

A: The acid-fast staining technique is a differential staining technique. The bacteria which get staine...

Q: Identify the causative agent of acquired immunodeficiency syndrome.

A: A disease is a particular abnormal condition that negatively affects the function or structure of al...

Q: What kind of things are able to cause genetic mutations?

A: Mutations arise due to permanent alterations occurred in the genotypes of organisms which cause sudd...

Q: In humans, the number of chromosomes per set equals 23. Eventhough the following conditions are leth...

A: Chromosomes are the thread like structures which contains packed DNA present inside the nucleus of a...

Q: Why are oceans least productive?

A: Production is the primary function of the ecosystem. An ecosystem maintains its component, biotic, a...

Q: Parents = B+ and AB- Given these are b.g. of parents. If they have a child, what blood types he/she ...

A: To determine the blood group of the upcoming generation Karl Landstiener came up with the ABO blood ...

Q: What is the molecular explanation for maternal effect?a. The father’s gene is silenced at fertilizat...

A: The maternal-effect is the influence on the phenotypic expression in an embryo or progeny due to the...

Q: MAKE CONNECTIONS The restriction site for an enzymecalled PvuI is the following sequence:5’-CGATCG-3...

A: The enzyme that recognizes the specific and short sequence of nucleotides and cut at that site is ca...

Q: A human disease known as vitamin D–resistant rickets isinherited as an X-linked dominant trait. If a...

A: Sex determination is the process by which an individual develops into a female or a male. The chromo...

Q: what causes Organellar Inheritance

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that con...

Q: Bacteria are capable of rapid ______________, and as a resultthese organisms vary enormously in size...

A: Bacteria consist of all the characteristics of a living being and can reproduce independently via th...

Q: How can adults continue to function relatively normally after surgeryto remove the thymus, tonsils, ...

A: Lymphatic system is a compartmentalized network of vessels, cells, and specialized accessory organs....

Q: Do all mammals have aplacenta?

A: Placenta is the organ that develops in the uterus during pregnancy. This structure is essential for ...

Q: Did Aphids Acquire Their Ability to Make CarotenoidsThrough Horizontal Gene Transfer?

A:   Aphids refer to the small insects that belong to the Aphidoidea superfamily. Aphids are sap-suckin...

Q: What is shape of lens during near vision and distinct vision.

A: The biconvex transparent structure in the eye is the lens. It facilitates the refraction of light to...

Q: QUESTION 6 Relative to an ectotherm, advantages (A) and disadvantages (D) for being an endothern ind...

A: Thermoregulation is an important aspect of regulating homeostasis. It involves the regulation of int...

Q: In general, what are the effects of histone acetylationand DNA methylation on gene expression?

A: Modification of DNA and the associated proteins is one of the mechanisms of regulation of gene expre...

Q: Which of the following would be used by a cell to signal cells close by? You can choose multiple a...

A: Cell signaling is the process of cell communication within the body. It is the ability of cells that...

Q: Which gas was released during bhopal tragedy?

A: The Bhopal disaster, which is also referred to as Bhopal gas tragedy, was a gas leak incident on the...

Q: Define the following terms: neuron, axon, dendrite, myelin sheath, afferent neuron, efferent neuron,...

A: Introduction  Neuron: A neuron is a single nerve cell which consists of central cell body, terminal ...

Q: What is the difference  Between a silent mutation and a neutral mutation?

A: Mutations are the alterations or the changes that occur in the DNA. Mutations are variations in codo...

Q: Give the dihybrid ratio. Name and state the law which explain the same.

A: Genetics is the branch of Biology dealing with the study of genes including their structure, functio...

Q: Explain how ribosomes and the nucleolus are related.

A: The structure of the cell was first observed and analyzed by Robert Hooke. The cell structure is com...

Q: A true-breeding tall pea plant was crossed to a true-breeding dwarfplant. What is the probability th...

A: According to Mendelian inheritance, a single character is controlled by one or more genes and each g...

Q: Is the mammalianembryonic development director indirect?

A: The process of embryonic development is otherwise known as embryogenesis. Fertilization is the initi...

Q: Summarize the transmission and pathology of the hepatitis C virus.

A: Hepatitis is a viral infection of the liver characterized by inflammation and necrosis. It interfere...

Q: Would it be proper to say that a patient has been disinfected? Why orwhy not?

A: The chemical treatment is the process in which disinfecting compounds like chlorine is added to kill...

Q: How do chaperones assist the Escherichia coli cell to makenitrate reductase?

A: In molecular biology, chaperones are specific proteins which assist the conformational folding or un...

Q: A brown mouse is mated to a white mouse and all of their offspring are brown. Define and assign symb...

A: INTRODUCTION: WHEN A BROWN MOUSE IS MATED WITH WHITE MOUSE When a brown mouse is mated with white mo...

Q: Differentiate between cerebrum and spinal cord on the basis of arrangement of cytons and axons of ne...

A: The brain is the main part of the body that controls every action in our body. It is located in the ...

Q: How does a cecal animal comparewith a ruminant?

A: Ruminants are mammalian animals that are foregut fermenters. Some of them are domestic animals. The ...

Q: The _______________________ at the inferior end of the sacrum is composed of several fused vertebrae...

A: Sacrum is a bone which is located at the upper back part of the pelvic cavity. It is large and trian...

Q: What is the purpose of the targeting vector?

A: In molecular cloning, vector is a segment of DNA molecule, which is used as an artificial carrier of...

Q: how a plant breeder can exploit situations of high heritability to improve a crop by artificial sele...

A: Plant breeding is the artificial selection of the desired traits, it also involves the genes exchang...

Q: Describe the process of X-chromosome inactivation in mammals

A: X-chromosome inactivation, also known as lyonization, is a process by which one of the copies of the...

Q: Contrast the habitats of Zygomycota and Glomeromycota.

A: Introduction  Zygomycota Phylum belongs to Kingdom Fungi and have around 1000 of species present thr...

Q: When glucocorticoids are prescribed using “twice a day” dosing, the doses should be divided in the f...

A: Glucocorticoids are corticosteroids, which are a class of steroid hormones. Glucocorticoids are powe...

Q: What is Thymine state its function.

A: DNA is deoxyribonucleic acid, which is a nucleic acid. It has threadlike structure and is composed o...

Q: What foods or substances that can change the volume of a normal urine?

A: Urine is a liquid by-product of metabolism in many animals  and in humans. The path of urine flow is...

Q: The general steps in a viral multiplication cycle area. adsorption, penetration, synthesis, assembly...

A: A pathogen or infectious agent is a biological agent that causes illness or disease to its host. Gen...

Q: Why do ribosomes movealong mRNA duringtranslation?

A: Ribosomes are present in all cells eukaryotic and prokaryotic cells and function to synthesize prote...

Q: What happens in Telophase? Explain briefly.

A: Mitosis is a type of cell division, during which one cell gives rise to two genetically identical da...

Q: Summarize the methods that located DNA in chromosomes.

A: Chromosomes are thread-like structures located inside the nucleus of plant and animal cells. Each ch...

Q: Plants that have acclimated to drought stress are often more resistantto freezing stress as well. Su...

A: The adaptation of organisms to adjust, survive, and perform normal activities at different environme...

Q: What is a Nucleoid made of?

A: A nucleoid is found inside a prokaryotic cell. Prokaryotes are a microscopic unicellular organism th...