Which of the following is absolutely true in case of arsenate poisoning
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A: True/False statements regarding the glycolysis with explanation.
Arsenate can replace inorganic phosphate in the reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase, causing glyceraldehyde-3-phosphate to be directly converted to 3-phosphoglycerate(NADH is still formed). Which of the following is absolutely true in case of arsenate poisoning
-Glycolysis will stop
- Glycolysis will still proceed with no net ATP gain
- Glycolysis will not generate any form of energy
- Glycolysis will still proceed, but with a net consumption of ATP
- Glycolysis will proceed with lactate as end product
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- The steps of glycolysis between glyceraldehyde 3-phosphate and 3-phosphoglycerate involve all of the following except: a. ATP synthesis. b. catalysis by phosphoglycerate kinase. c. oxidation of NADH to NAD+. d. the formation of 1,3-bisphosphoglycerate. e. utilization of Pi.In the last step of glycolysis, phosphoenolpyruvate (PEP) is converted to pyruvate and during this reaction ATP is synthesized. Based on the fact that ATP is synthesized, which of the following enzymes would most likely catalyze this reaction? a. enolase b. pyruvate kinase c. aldolase d. pyruvate isomerase e. pyruvate dehydrogenaseWhich of the following catalyzes a step that does NOT produce CO2? Group of answer choices alpha-ketoglutarate dehydrogenase complex malate dehydrogenase pyruvate dehydrogenase complex isocitrate dehydrogenase Citrate synthase is regulated by... Group of answer choices Concentrations of substrate and products Fructose-2,6-Bisphosphate Covalent modification Allosteric regulation by the levels of NADDH
- iodoacetate is an irreversible inhibitor of glyceraldehyde-3-phosphate dehydrogenase. which of the following is the expected outcome of the exposure of a cell to iodoacetate - Cellular resiration will stop if the cell solely depends on glucose as fuel - The rate of cellular respiration will increase - The reoxidation of coenzymes will noy be affected , but the efficiency of oxidative phosphorylation will be diminished - There will be no effect on cellular respiration as long as the cell has a large glucose reserve -The cell sill not be able to reoxidize the reduced coenzymesWhich of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinaseDuring strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is: a. dihydroxyacetone phosphate → glycerol 3-phosphate b. glucose 6-phosphate → fructose 6-phosphate c. isocitrate → α-ketoglutarate d. oxaloacetate → malate e. pyruvate → lactate
- In the glycolysis, the only redox reaction “glyceraldehyde 3-phosphate → 1,3-bisphosphoglycerate” (enzyme: glyceraldehyde 3-phosphate dehydrogenase) involves all of the following EXCEPT the: Question 13 options: formation of 1,3-bisphosphoglycerate utilization of inorganic phosphate as a reactant reduction of NAD+ to NADH utilization of ATP as a reactant oxidation of glyceraldehyde 3-PhosphateThe glycolytic enzyme pyruvate kinase catalyzes the conversion of: 1,3-bisphosphoglycerate into 3-phosphoglycerate (producing ATP) glyceraldehyde-3-phosphate into 1,3-bisphosphoglycerate (producing NADH) phosphoenolpyruvate into pyruvate (producing ATP) fructose-6-phosphate into fructose-1,6-bisphosphate (consuming ATP) glucose into glucose-6-phosphate (consuming ATP)The Glycolytic pathway describes the oxidation of glucose to pyruvate with the generation of ATP and NADH Which of the following 8 statements are correct about the process of Glycolysis? a.Dihydroxyacetone phosphate is isomerized to the aldehyde glyceraldehyde 3-phosphate b. phosphoenolpyruvate is formed from the loss of a hydrogen atom on carbon 2 and a hydroxyl group from carbon 3 c. Glucose transporters only transports phosphorylated glucose d. 2 molecules of NADH is produced from the phosphorylated oxidation of Glyceraldehyde-3-phosphate e. when phosphoenolpyruvate is converted to pyruvate, 1 molecule of ATP is produced f. Fructose-1,6.biphosphate is cleaved by aldolase to form 2 molecules of glyceraldehyde-3-phosphate g. The substrate level phosphorylation of 1,3-biphosphoglycerate yields 2 molecules of ATP h. Glyceraldehyde-3-phosphate loses a hydrogen atom on carbon 1 and gains an oxygen atom i. The ketose sugar glucose-6-phosphate is…
- During which of the following conversions is NADH+H+ formed in the glycolysis cycle? a. Glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate b. 1,3-bisphosphoglycerate to 3-Phosphoglycerate c. 2-Phosphoglycerate to Phosphoenolpyruvate d. Phosphoenolpyruvate to PyruvateGlyceraldehyde 3-phosphate dehydrogenase is used to do which of the following steps of glycolysis Select one: a. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate b. Phosphoenolpyruvate is converted to pyruvate c. 2-phosphoglycerate is converted to Phosphoenolpyruvate d. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate e. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphate f. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate g. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate h. Glucose-6-phosphate is converted to Fructose-6-phosphate i. 3-phosphoglycerate is converted 2-phosphoglycerate j. Glucose is converted to Glucose-6-phosphateWhat yield of ATP can be expected from complete oxidation of each of the following substrates by the reactionsof glycolysis, the citric acid cycle, and oxidative phosphorylation?(a) Fructose-1,6-bisphosphate(b) Glucose(c) Phosphoenolpyruvate(d) Glyceraldehyde-3-phosphate(e) NADH(f) Pyruvate