Which of the following pairings of genotypes is a concern for the health of the baby in regards to Rh factor? mom Rh-pos (++) and dad Rh-neg (--) mom Rh-neg (--) and dad Rh-pos (++) mom Rh-pos (+-) and dad Rh-pos (+-) mom Rh-neg (--) and dad Rh-neg (--)
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Which of the following pairings of genotypes is a concern for the health of the baby in regards to Rh factor?
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mom Rh-pos (++) and dad Rh-neg (--) |
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mom Rh-neg (--) and dad Rh-pos (++) |
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mom Rh-pos (+-) and dad Rh-pos (+-) |
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mom Rh-neg (--) and dad Rh-neg (--) |
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- Given: Father - heterozygous for the H locus of the H antigen, heterozygous for the B locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and deuteranope Mother - heterozygous for the H locus of the H antigen, heterozygous for the A locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and carrier for the trait deuteranopia Task: Using the line fork method, determine the probabilities in ratio form of all possible phenotype combinations of the traits in the biological offspring of the couple. Include the solutionBarbara and John have two daughters (Madison and Kelly), and one son (Mike), all have normal red blood cells. Their other son (Chase) has been diagnosed with sickle cell. Barbara recently gave birth to another son (Barry) who also has been diagnosed with sickle cell. Barbara’s mother (Beth) has sickle cell, but her father (Jason), three sisters (Emma, Lori, and Allison), and two brothers (Emmitt and Will) are all normal. John’s father (Jim), mother (Brenda), and brother (Parker) are all normal, but his sister (Demi) has sickle cell. John’s maternal grandparents (Bill and Lonna) are carriers. Barbara’s paternal grandparents (Kevin and Martha) are all normal. make an pedigreeBarbara and John have two daughters (Madison and Kelly), and one son (Mike), all have normal red blood cells. Their other son (Chase) has been diagnosed with sickle cell. Barbara recently gave birth to another son (Barry) who also has been diagnosed with sickle cell. Barbara’s mother (Beth) has sickle cell, but her father (Jason), three sisters (Emma, Lori, and Allison), and two brothers (Emmitt and Will) are all normal. John’s father (Jim), mother (Brenda), and brother (Parker) are all normal, but his sister (Demi) has sickle cell. John’s maternal grandparents (Bill and Lonna) are carriers. Barbara’s paternal grandparents (Kevin and Martha) are all normal Paternal = a person’s dad’s side of the family Maternal = a person’s mom’s side of the family 1. Draw a pedigree to show how this trait could affect this family within each generation 2. Shade all individuals affected with the disorder. Half shade all carriers. 3. Assign genotypes to every individual. Use Punnett squares to…
- Below are the ABO and Rh blood types of some couples. If during birth some blood is exchaged between the mother and the first newborn, the second newborn of which couple has the LEAST chance for suffering from hemolytic disease of the newborn due to Rh incompatibility? Consider both Rh and ABO incompatibilities. A. Wife B -, husband O + B. Wife AB -, husband AB + C. Wife AB -, husband O+ D. Wife O -, husband B + E. Wife A -, husband O+Why is the agglutination seen in Rh finer than that seen in groups A and B?A phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac?
- Kara is B-positive and her father has A-negative blood. Kara marries Ryan, who is A-negative. Ryan’s father has O-positive blood. (e)What are the phenotypic ratios of blood types (for both the ABO gene and Rh gene) that would be expected among their children? (Show your work in a Punnett square below!)Please use instructions from above Hemophilia is an x-linked disease of the blood. What is the probability of producing an unaffected son by a father who is unaffected and a mother who is a carrier of hemophilia?A child with the "B positive” blood type is known to be a heterozygote at both the ABO blood type gene and also the Rh blood type gene. What is the genotype of this child at these two genes?
- Alice has type A blood and her husband Mark has type B blood. Their first child, Amanda, has type O blood. Their second child, Alex, has type AB blood. What is Alice's genotype?Rh factors are proteins that were first discovered in the blood of Rhesus Monkeys, but humans have them too. If you are Rh positive, it means that there are Rh type proteins in your blood. If you are Rh negative, there are no Rh type proteins in your blood. Positive is dominant over negative, so heterozygous individuals are Rh positive. Problems can arise when an Rh negative mother has a child who is Rh positive. Which of the statements will answer the following questions: Why does the mother's body attack her own baby in this situation? Why does the situation get worse for the second pregnancy? a. The mother's body sees the foreign proteins produced by her baby as a threat. She builds up antibodies against them. b. Her immune system attacks the baby, often resulting in a miscarriage. Immune suppressing drugs can be given to the mom, but then she's more likely to get sick because her body's germ fighting ability is diminished. c. The baby is delivered before the situation gets too…Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the blood-clotting pathway. Shown above is a family pedigree tree in which family members afflicted with the disease are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passing on the disease to their future children (represented by the ? symbol above) because the hemophilia runs in the woman’s family 4.Assuming that the woman in the couple is a carrier, what is the probability that the couple’s first son will have hemophilia?
