Which statement describes a limitation of T-cell receptors (TCRs) compared to B-cell receptors (BCRs)? A.) only BCRs can interact with epitopes on free antigens or epitopes B.) displayed directly on the pathogen C.) only BCRs can initiate a pathogen-specific immune response D.) only BCRs recognize pathogen epitopes

Which statement describes a limitation of T-cell receptors (TCRs) compared to B-cell receptors (BCRs)? A.) only BCRs can interact with epitopes on free antigens or epitopes B.) displayed directly on the pathogen C.) only BCRs can initiate a pathogen-specific immune response D.) only BCRs recognize pathogen epitopes

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter17: The Immune System And Disease

Section: Chapter Questions

Problem 19CTQ: If a series of genetic mutations prevented some, but not all, of the complement proteins from...

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Which of these statements about complement proteins C3a and C5a is false?a. They are released during the complement fixation process.b. They stimulate chemotaxis of phagocytic cells.c. They promote the activity of phagocytic cells.d.They produce pores in the victim plasma membrane.
Many cells in the human body have proteins on the surface that are able to interact with the receptors of helper T cells. Explain the mechanisms and why it is that such an interaction or signal does not usually result in an autoimmune reaction?
Explain the two processes by which B-cells are activated to inactivate an antigen?
Activated helper T Cells participate in which of the following processes? a.) Differentiation of memory B cells b.) Activation of cytotoxic T Cells c.) Facilitation of macrophage phagocytosis d.) All of above
Choose the most accurate characteristic of B cells. A) They help establish and control the sensitivity of the immune response. B) They stimulate the activities of T cells. C) They attack foreign cells, normal cells infected with viruses, and cancer cells that appear in normal tissues. D) They continually monitor peripheral tissues. E) They differentiate into plasma cells that secrete antibodies.
A patient has contracted an upper respiratory infection caused by a virus. Her initial adaptive immune response to the virus is due to what mechanism of immune surveillance?a. The display of viral antigens by naïve B-cells on class I MHC, which is then recognized by helper T-cells that then activate cytotoxic T-cells.b. The display of viral antigens on class I MHC, which is then displayed to sensitized naïve B-cells, leading to the production of antibodies.c. The display of viral antigens on class II MHC by a sensitized naïve B-cell, which is then activated by a helper T-cell primed to the same antigen to begin producing antibodies.d. The display of viral antigens on class I MHC, which is then displayed to helper T-cells, leading to the activation of naïve cytotoxic T-cells.
Adaptive immunity includes both humoral and cell-mediated immune responses, which interact but also have distinct roles in adaptive immunity. Identify the example of a strictly cell-mediated immune response. A. A cytotoxic T cell destroys an infected host cell. B. A helper T cell activates a B cell. C. A B cell gives rise to plasma cells, which release antibodies. D. An antigen is taken in by an antigen-presenting cell.
What is the difference between a T-cell-dependent and T-cell- independent response?
If a given B cell produces only one type of antibody, how do organisms produce a great diversity of antibodies?
In the process shown in Diagram 2, what performs the function most similar to that of the activated T cell in Diagram 1?
Which of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.
Explain the reason that T-cells are so critical in recognizing and destroying virally-infected host cells.