Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to answer this. To which chemical groups do these amino acids belong? Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules!

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Exercise B: Peptide Bond Formation
Figure 3 shows two individual amino acids, and then those same two amino acids after
they have been linked together by a peptide bond to form a dipeptide. Addition of
more amino acids linked by peptide bonds would form a polypeptide, the precursor to a
functional protein.
нн
H
H O
нно
H O
+| | ||
H-N-C-ċ-o +
+| 1 ||
H-N-C-C
+| | ||
Н-N—С- С—N—C—С
H
CH2
H
CH2
H
CH2
CH2
SH
SH
NH2
NH2
Figure 3. Formation of a peptide bond between two amino acids.
Answer the below questions in your own document.
• Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to
answer this.
• To which chemical groups do these amino acids belong?
Were you able to identify their chemical characteristics based on your rules? If
not, you should go back and revise your rules!
On the dipeptide shown in Figure 3, label the peptide bond that was formed when the
two individual amino acids were joined. Label the free amino and carboxyl groups at
the ends of this dipeptide (not in the R groups). These are often referred to as the N-
terminus (amino-terminus) and the C-terminus (carboxyl-terminus) of a peptide or
polypeptide. (Note: "peptide" refers to a chain of a small number of amino acids,
whereas "polypeptide" refers to a longer chain, potentially that corresponding to an
entire protein.)
Screenshot
Transcribed Image Text:Exercise B: Peptide Bond Formation Figure 3 shows two individual amino acids, and then those same two amino acids after they have been linked together by a peptide bond to form a dipeptide. Addition of more amino acids linked by peptide bonds would form a polypeptide, the precursor to a functional protein. нн H H O нно H O +| | || H-N-C-ċ-o + +| 1 || H-N-C-C +| | || Н-N—С- С—N—C—С H CH2 H CH2 H CH2 CH2 SH SH NH2 NH2 Figure 3. Formation of a peptide bond between two amino acids. Answer the below questions in your own document. • Which two amino acids are shown on the left side of Figure 3? Use Figure 2 to answer this. • To which chemical groups do these amino acids belong? Were you able to identify their chemical characteristics based on your rules? If not, you should go back and revise your rules! On the dipeptide shown in Figure 3, label the peptide bond that was formed when the two individual amino acids were joined. Label the free amino and carboxyl groups at the ends of this dipeptide (not in the R groups). These are often referred to as the N- terminus (amino-terminus) and the C-terminus (carboxyl-terminus) of a peptide or polypeptide. (Note: "peptide" refers to a chain of a small number of amino acids, whereas "polypeptide" refers to a longer chain, potentially that corresponding to an entire protein.) Screenshot
have in common so that you will be able to identify the chemical group for each of
the 20 amino acids if you are shown its structure. Record your rules in a table
similar to the one shown below.
Nonpolar
Polar (uncharged)
COO
COO
COO"
H3N-C-H
HN-C-H
HạN-C -H
H3N -C -H
HaN-C-H
H3N-C-H
H
CH3
CH
バ
CH,OH
H-C-OH
CH2
CH, CH,
CH3
SH
Glycine
Alanine
Valine
Serine
Threonine
Cysteine
COO
COO
COO
HaN-C-H
HN-C-H
HN-C-H
COO
CH2
CH2
H-C-CH3
HN-C-H
CH
CH2
CH,
CH2
CH2
CH; CH3
CH3
CH2
CH3
H2N
Leucine
Methionine
Isoleucine
Coo
COo-
Coo
Asparagine
Glutamine
H3N-C-H
HN-C -H HN-c-H
Basic
CH2
CH2
CH2
COO
CO"
C=CH
HN-C-H
-C-H
-C-H
NH
CH,
CH2
CH2
ÓH
CH2
CH2
C-NH
CH
CH2
CH2
C-NA
Phenylalanine
Tyrosine
Tryptophan
CH2
NH
CO-
*NH3
C3D
NH2
CH,
Lysine
Arginine
Histidine
HC CH2
Acidic
COO
CO0
Proline
HN-C-H
HạN-C-H
CH2
CH2
COO
CH2
CO0
Aspartate
Glutamate
Figure 2. Structures of the 20 natura
mino acids.
Screenshot
Transcribed Image Text:have in common so that you will be able to identify the chemical group for each of the 20 amino acids if you are shown its structure. Record your rules in a table similar to the one shown below. Nonpolar Polar (uncharged) COO COO COO" H3N-C-H HN-C-H HạN-C -H H3N -C -H HaN-C-H H3N-C-H H CH3 CH バ CH,OH H-C-OH CH2 CH, CH, CH3 SH Glycine Alanine Valine Serine Threonine Cysteine COO COO COO HaN-C-H HN-C-H HN-C-H COO CH2 CH2 H-C-CH3 HN-C-H CH CH2 CH, CH2 CH2 CH; CH3 CH3 CH2 CH3 H2N Leucine Methionine Isoleucine Coo COo- Coo Asparagine Glutamine H3N-C-H HN-C -H HN-c-H Basic CH2 CH2 CH2 COO CO" C=CH HN-C-H -C-H -C-H NH CH, CH2 CH2 ÓH CH2 CH2 C-NH CH CH2 CH2 C-NA Phenylalanine Tyrosine Tryptophan CH2 NH CO- *NH3 C3D NH2 CH, Lysine Arginine Histidine HC CH2 Acidic COO CO0 Proline HN-C-H HạN-C-H CH2 CH2 COO CH2 CO0 Aspartate Glutamate Figure 2. Structures of the 20 natura mino acids. Screenshot
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