white b. light black c. medium TA I. X-LINKED OR SEX-LINKED TRAITS A color-blind man marries a woman wit blind. Use aXfor normal vision, and al X for color-blindness, (Remember where sex-linked traits are carried). What is the genotype of the ma al vision, whose father was color- h norm type of the manand woman? Use a Punnett square to show the phenotypes of their progeny 172

white b. light black c. medium TA I. X-LINKED OR SEX-LINKED TRAITS A color-blind man marries a woman wit blind. Use aXfor normal vision, and al X for color-blindness, (Remember where sex-linked traits are carried). What is the genotype of the ma al vision, whose father was color- h norm type of the manand woman? Use a Punnett square to show the phenotypes of their progeny 172

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 20QP: Analysis of X-Linked Dominant and Recessive Traits The following is a pedigree for a common genetic...

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Analysis of X-Linked Dominant and Recessive Traits A young boy is color-blind. His one brother and five sisters are not. The boy has three maternal uncles and four maternal aunts. None of his uncles children or grandchildren is color-blind. One of the maternal aunts married a color-blind man, and half of her children, both male and female, are color-blind. The other aunts married men who have normal color vision. All their daughters have normal vision, but half of their sons are color-blind. a. Which of the boys four grandparents transmitted the gene for color blindness? b. Are any of the boys aunts or uncles color-blind? c. Is either of the boys parents color-blind?
Eye Color (B, b) (B dominant for brown eyes; b for blue eyes) If Mrs. Spud's genotype is Bb and Mr. Spud's genotype is bb. What would be the genotype for baby Spud?
BbRrppMm X bbRrPpMM: probability of producing an individual that is dominant for B & M and recessive for R and P?
.Certain forms of human color blindness are inherited as X-linkedrecessive traits. Hemizygous males are color-blind, but heterozygous females are not. However, heterozygous females sometimeshave partial color blindness.A. Discuss why heterozygous females may have partial color blindness.B. Doctors identified an unusual case in which a heterozygousfemale was color-blind in her right eye but had normal colorvision in her left eye. Explain how this might have occurred.
Classical hemophilia is a sex-linked disease caused by a recessive gene on the X chromosome. (Hemophilia refers to diseases that cause delays in blood clotting.) If a woman who is acarrierof classical hemophilia has children with a normal male, give the ratios of the possible offspring with respect to classical hemophilia. Be sure to state both the genotypes and the phenotypes of each offspring. For genotypes, use X for a normal X chromosome, Xh for an X chromosome with the hemophilia gene, and Y for a normal Y chromosome. For phenotypes, if the offspring is female, be sure to state if homozygous normal, a carrier, or has the disease. If the offspring is a male, be sure to state if normal or has the disease.
Analysis of Autosomal Recessive and Dominant Traits Huntington disease is a rare, fatal disease that usually develops in the fourth or fifth decade of life. It is caused by a single autosomal dominant allele. A phenotypically normal man in his twenties who has a 2-year-old son of his own learns that his father has developed Huntington disease. What is the probability that he himself will develop the disease? What is the chance that his young son will eventually develop the disease?
Analysis of X-Linked Dominant and Recessive Traits The following is a pedigree for a common genetic trait. Analyze the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linked
More Crosses with Pea Plants: The Principle of Independent Assortment Determine the possible genotypes of the following parents by analyzing the phenotypes of their children. In this case, we will assume that brown eyes (B) is dominant to blue (b) and that right-handedness (R) is dominant to left-handedness (r). a. Parents: brown eyes, right-handed brown eyes, right-handed Offspring: 3/4 brown eyes, right-handed 1/4 blue eyes, right-handed b. Parents: brown eyes, right-handed blue eyes, right-handed Offspring: 6/16 blue eyes, right-handed 2/16 blue eyes, left-handed 6/16 brown eyes, right-handed 2/16 brown eyes, left-handed c. Parents: brown eyes, right-handed blue eyes, left-handed Offspring: 1/4 brown eyes, right-handed 1/4 brown eyes, left-handed 1/4 blue eyes, right-handed 1/4 blue eyes, left-handed
Analysis of Autosomal Recessive and Dominant Traits Describe the phenotype and primary gene or protein defect of the X-linked recessive disease muscular dystrophy.
Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linked
In humans color vision is X-linked, the gene for color vision is located on the X chromosome but is absent on the Y chromosome. Normal color vision (XN) is dominant over colorblindness (Xn). Suppose a colorblind man fathers the children of a woman with genotype XNXN. What is the genotype of the father? What proportion of daughters will be colorblind? What proportion of the sons will be colorblind?
Colorblindness is an X linked gene. Normal vision (XN ) is dominant over colorblind (Xn). Cross a carrier female to a normal male. How many of their children will be colorblind? How many of their sons will be colorblind? How many of their daughters will be colorblind?