Why is a sulfonate anion such a good leaving group?

Q: Why an anhydride is less reactive than an acyl chloride?

A: The reactivity of acyl chloride and acid anhydride occurs due to the electrophilicity of carbonyl…

Q: In Synthesis of Diben zalacetone, why does the reaction end up being fully conjugated at the…

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Q: Why is this considered an Elimination E2 reaction? C₃H₈O (l)  → C3H6 (g) + H2O (l) propan-1-ol…

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Q: Trimethylphosphine is a stronger nucleophile than triphenylphosphine, but it is rarely usedto make…

A: Given data :   Trimethylphosphine is a stronger nucleophile than triphenylphosphine, but it is…

Q: What reagent did you use alongside with the peroxide on the first reaction?

A: Here, I have shown all the reagents that are involved in reaction one with names.

Q: why is 12 M HCl added to the reaction mixture after the Williamson Ether Synthesis r

A: Williamson ether synthesis is used to prepare both symmetrical and unsymmetrical ether. When sodium…

Q: Why is the N-H bond of an imide especially acidic?

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Q: Offer an explanation for the observation that 4-chloropyridine is more reactive toward nucleophiles…

A: The reason why 4-chloropyridine is more reactive towards nucleophiles when compared to…

Q: Draw a resonance structure that explains the unusual stability of the byproduct in the Gabriel…

A: Resonance structure:If the Lewis structure of a molecule or ion cannot explain by a single structure…

Q: HNO3 Zn A B D H2SO4 HCI or

A: The benzene undergoes an electrophilic substitution reaction. It has a high electron density, as it…

Q: What are the minor products of the preceding Hofmann elimination reaction?

A: The minor product of the preceding Hofmann elimination reaction has to be determined.

Q: why is tylenol ( acetaminophen) not a good nucleophile to make a good nuclophile what reaction does…

A: Using Williamson ether synthesis we can synthesized phenacatin from tylenol.  Tylenol is not good…

Q: Which solvent would have a higher reaction rate for SN1? acetone ethanol Why does the solvent you…

A: Ethanol is a polar solvent that is used in SN1 reactions.

Q: According to the resonance form, why is 2-nitrobenzoic acid stronger than benzoic acid?

A: A compound is composed of certain bonding between different atoms. The arrangement of atoms in a…

Q: How does the reactivity of an aldehyde or a ketone toward nucleophiles compare with thereactivity of…

A: Aldehydes are generally more reactive than ketones in nucleophilic addition reactions due to steric…

Q: If the reaction to baeyer's reagent is positive, the internal alkyne would be transformed into…

A: Baeyer's Reagent -  It is an alkaline solution of cold potassium permanganate.

Q: In the Iodination of Acetone, What will happen to the reaction time and reaction rate if the…

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Q: Which solvent would be used for a reaction using a Grignard reagent (RMgX)?

A: The solvent with no acidic hydrogen is used in case of grignard reagent reaction.

Q: Explain the effect of protic solvents in SN1 Reaction.

A: The effect of protic solvents in the SN1 Reaction has to be explained below.

Q: 3. Why does the aldehyde structure used as the starting material in the Wittig synthesis cannot have…

A: Given: Aldehyde structure used as a starting material in the wittig synthesis To find: why…

Q: What is the first step in the mechanism of the reaction of DIBAL-H with an ester?

A: DIBAL-H  = Di isobutyl aluminum hydride  Reducing agent It reduce ester to aldehyde (also reduce…

Q: How may methyl bromide be preferentially converted to methyl isocyanide?

A: Given: Conversion of methyl bromide to methyl isocyanide

Q: Question 8 of 11 Suggest the starting material needed to make the ß-dicarbonyl compound by a Claisen…

A: Here we are required to find the Starting material needed to form beta dicarbonyl ester

Q: Choose the starting materials needed to complete this Robinson annulation reaction. Assume an acidic…

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Q: Which of the following would be suitable to use when forming a Grignard reagent? Put a circle HO Br…

A: Grignard reagents are widely used in chemical reactions to produce different compounds by reacting…

Q: 5. Using pictures and words, explain why triflate, CF3SO3, is such a good leaving group.

A: To explain why triflate, CF3SO3- is such a good leaving group using pictures and words.

Q: What is the likely mechanism of nucleophilic substitution for attached alkyl halide?

A: Alkyl halides undergo nucleophilic substitution reactions. Nucleophilic substitution reactions are…

Q: What is the common of the chromium containing group, the per-iodinane, and the dimethy! sulphide in…

A: per-iodinane oxidiase carbonyl groups into carboxylic acid.

Q: Explain Reaction of Grignard Reagents with Carbon Dioxide ?

A: Grignard reagent It is also known as grignard compound. It has generic formula R-Mg-X. X is halogen.…

Q: 4. Why is it unwise to begin addition of the solution of carbonyl compound to the Grignard reagent…

A: Organic reactions are the chemical reactions in which certain organic compounds involve in chemical…

Q: While attempting to recrystallize maleic anhydride, a student dissolved it in freshly distilled…

A: Cyclopentadiene is a conjugated diene that is used in the Diels alder Reaction. Diels Alder Reaction…

Q: Which solvent would be the best choice (DMF, methanol, or acetic acid) to carry out the nucleophilic…

A: There are different types of nucleophilic substitution reaction-  1- SN1 reaction 2- SN2 reaction

Q: What is the most likely dehydration product of the following reaction?

A: The question is based on the concept of organic reactions.   We have to identify the product formed…

Q: Consider the reaction sequence shown in the box. The intermediate of the reaction sequence is an…

A: A Gilman reagent is a lithium and copper (diorganocopper) reagent compound, R2CuLi.

Q: hy is bromination more selective than chlorination?

A: bromination more selective than chlorination because

Q: What is the function of N-bromosuccinimide in allylic bromination reactions?

A: N-bromosuccinimide (NBS) is the reagent that furnishes "electrophilic addition reactions" or…

Q: How the rate of reaction is slows down when 2-methyl groups from t-butylcation are replaced by…

A: The rate of the reaction depends upon many factors. Some of them are: 1. Reactant concentration. 2.…

Q: Why are enolates more usful than enols ?

A: Enolates more useful than enols have to be determined.

Q: Why is the ortho-carboxy substituent a general-base catalyst in one reaction and a nucleophilic…

A: When the carboxy group is at ortho it is in the place where it can easily accept a proton from water…

Q: 5. Briefly explain your answer to the previous question in terms of the merits or drawbacks of each…

A: The suitable reagent for the conversion of R(CO)Cl to R(CO)CH3, (CH3)2CuLi is used.

Q: ith an equivalent of R1 in

A: Species which are electron rich acts as nucleophile. They have a strong tendency to attack at a…

Q: Explain how these Grignard reagents would react with molecules of their own kind to “self-destruct.”

A: 3-Hydroxypropylmagnesium bromide has an acidic proton (the alcohol). Because Grignard reagents are…

Q: Define the carbon bond-forming reactions of enolates with carbonyl electrophiles ?

A: The chemical moiety formed by the deprotonation from the α-carbon atom of a ketone/aldehyde is…

Q: Reduction of Cinnamaldehyde lab What is the purpose of adding sodium bisulfite?

A: The dilute sodium bisulfite solution is used to form salt andbit is carried out by the addition…

Q: 1. Compare the mechanism of the addition of Grignard reagent and Witting reagent to the carbonyl…

A: Applying concept of organic synthesis.

Q: Why is the overacylation of benzene not a problem when subjecting benzene to a Friedel-Crafts…

A: Using advantage of fredalcraft acylation reaction.

Q: An alkene with electron withdrawing group is a good dienophile?

A: * Diels alder reaction occur between diene and     dienophile. *Dienophiles are electron deficient…

Q: How does changing the halide from (CH3)3CBr to CH3CH2CH2Br affect the rate of an E1 reaction?

A: E1 reaction proceeds with a two step mechanism where the first step is the formation of carbocation…