Asked Nov 24, 2019

Why would the differential renal vein renin test show an increase in the blocked renal artery side secretion of renin, yet a drop in renin levels on the other (normal) side?


Expert Answer

Step 1

Renal vein renin test measures the ratio between the ischemic kidney and that of contralateral kidney. A ratio more than 1.5 indicates positive test result and there exists a functionally important Reno vascular disease.

Step 2

The below listed four factors theoretically may affect the renal vein renin ratio in unilateral renal artery stenosis.

  • Increased renin secretion.
  • Diminished renal plasma flow on the stenotic side.
  • Suppressed renin secretion.
  • Renin extraction on the contralateral side.

In patients with unilateral renal a...

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