You are doing an experiment in which you are measuring the rate at which succinic acid is converted to fumaric acid by an enzyme succinic dehydrogenase because you want to design a drug that can block this step in the metabolic pathway of a pathogenic bacteria. You decide to add a little malonic acid  to make things interesting.. You observe that the reaction rate slows markedly and being a very smart graduate of Medgar Evers College, you conclude that malonic acid must be acting as an inhibitor. Design an experiment that will help you decide if malonic acid is acting as a competitive inhibitor or a noncompetitive inhibitor. Go to work and expect a promotion. Good luck.

Question
  1. Congratulations! You have just secured a great job in a pharmaceutical company.

You are doing an experiment in which you are measuring the rate at which succinic acid is converted to fumaric acid by an enzyme succinic dehydrogenase because you want to design a drug that can block this step in the metabolic pathway of a pathogenic bacteria. You decide to add a little malonic acid  to make things interesting.. You observe that the reaction rate slows markedly and being a very smart graduate of Medgar Evers College, you conclude that malonic acid must be acting as an inhibitor. Design an experiment that will help you decide if malonic acid is acting as a competitive inhibitor or a noncompetitive inhibitor. Go to work and expect a promotion. Good luck.

Expert Answer

Want to see the step-by-step answer?

Check out a sample Q&A here.

Want to see this answer and more?

Experts are waiting 24/7 to provide step-by-step solutions in as fast as 30 minutes!*

*Response times may vary by subject and question complexity. Median response time is 34 minutes for paid subscribers and may be longer for promotional offers.
Tagged in
Science
Biology

Biochemistry

Related Biology Q&A

Find answers to questions asked by students like you.

Q: Draw a picture that illustrates how DNA helicase works.

A: Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic info...

Q: What is the difference between the cloned animal and nuclear donors in terms of the uterine environm...

A: Step 1 A clone is a living organism that part the similar genetic information as the specific organi...

Q: The adrenal glands are attached superiorly to whichorgan? a. thyroidb. liverc. kidneysd. hypothalamu...

A: Adrenaline is an essential endocrine gland that is involved in secretion of hormones like adrenaline...

Q: Which of the following terms is the most broad?   a phenotype b characte...

A: Genetics is a branch of biology which deals with the study of genes, genetic variation, and heredity...

Q: how is the respiratory system involved in maintenance of acid base balance in human body

A: Click to see the answer

Q: Which of the following is true regarding where mitosis and meiosis occur within multicellular organi...

A: Actively divided cells go to the series of stages referred to as cell cycle. It is divided into four...

Q: What two processes ensure that the correct amino acidis added to a growing polypeptide chain?

A: The tRNA is a transfer RNA. It reads the nucleotide present on the mRNA and translates that mRNA int...

Q: What foods or substances that can change the volume of a normal urine?

A: Urine is a liquid by-product of metabolism in many animals  and in humans. The path of urine flow is...

Q: What happens to preload when there is venousconstriction in the veins?a. It increases.b. It decrease...

A: The heart is a muscular organ in most animals. It pumps blood through the blood vessels of the circu...

Q: What is tendril? Name any two types of tendrils.

A: Leaves are the structures on the plant which help the plants to carry out photosynthesis and produce...

Q: Which structure completes cytokinesis in bacterial cells?   Question 39 options:   con...

A: Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryot...

Q: What does the sex chromosome genotype XO produce in drosophilia?

A: Generally, there are two types of chromosomes namely autosomes and allosomes. Autosomes determine th...

Q: Which of the following prenatal genetic testing methods is donein conjunction with in vitro fertiliz...

A: In vitro fertilization (IVF) is a process of fertilization where an egg is combined with sperm outsi...

Q: While conducting field studies on a chain of islands, you decide tokaryotype two phenotypically iden...

A: When individuals of the same specie are geographically isolated, it may happen that the population b...

Q: Why do ribosomes movealong mRNA duringtranslation?

A: Ribosomes are present in all cells eukaryotic and prokaryotic cells and function to synthesize prote...

Q: Is colchicine a steroid?

A: Introduction: Colchicine is a drug that has the potential to treat gout or gout attacks. Gout is a m...

Q: Describe the key features of the Watson-Crick model for DNA structure?

A: Genetics is a branch of biology that deals with the study of genes, genetic variation, and heredity ...

Q: Relate how Mendel’s experimental approach is similar to the process of modern scientific inquiry.

A: Gregor Mendel was a scientist who worked in the field of molecular biology and genetics. These field...

Q: Discuss the down syndromr? Give its symptoms and cause?

A: Genetic disorder is caused due to genetic abnormalities. Down syndrome is a genetic disorder which v...

Q: In this chapter, we considered a computer program that translates aDNA sequence into a polypeptide s...

A: Translation is a process in which the conversion of DNA sequence into amino acid sequence takes plac...

Q: What is the ecological importance of fungi?

A: Fungi play an important role in the balance of the ecosystems. They have the capability of colonizin...

Q: Give some common examples of brown adipose tissue?

A: Brown adipose tissues are so named because of their brownish appearance and are found in mammals whe...

Q: Briefly describe light reaction.

A: Plants are mainly multicellular organisms, predominantly photosynthetic eukaryotes of the kingdom Pl...

Q: ELISA is used to detect viruses where the key reagent is?

A: Immunoassay is a technique that has the capability to detect even minute quantities of antigen or an...

Q: What do you mean by acrosome?

A: In most animals, the sperm is the male gamete that fuses with the female gamete and forms the diploi...

Q: Describe the origin and early evolution ofmammals.

A: Vertebrates have spinal cord which remain surrounded by bone or cartilage. Reptiles, birds, fish, am...

Q: Discuss the significance of modified bases within tRNA molecules.

A: There are four nucleotide bases present in DNA such as Adenine (A), Thymine (T), Guanine (G) and Cyt...

Q: Can decliningamphibianpopulations besaved by a vaccine?

A: Amphibians are the organism that belongs to the kingdom Animalia and are vertebrates that are ectoth...

Q: A human disease known as vitamin D–resistant rickets isinherited as an X-linked dominant trait. If a...

A: Sex determination is the process by which an individual develops into a female or a male. The chromo...

Q: Demonstrate the experiment to measure rate of transpiration by farmer's potometer.

A: A plant is known to uptake water to accomplish photosynthesis and transpiration. This water uptake b...

Q: What are vertibrates and its types?

A: INTRODUCTION: Vertebrates consist of all species of animals which are present in the subphylum verte...

Q: Explain how DNA microarrays are used in molecular profiling ofcancerous tumors.

A: DNA microarrays are microscopic slides that are printed with thousands of tiny spots in defined posi...

Q: When glucocorticoids are prescribed using “twice a day” dosing, the doses should be divided in the f...

A: Glucocorticoids are corticosteroids, which are a class of steroid hormones. Glucocorticoids are powe...

Q: Are bananas triploid?

A: A fruit that lacks the seed precisely mature seeds is called seedless fruit. Some of the common exam...

Q: Which gas was released during bhopal tragedy?

A: The Bhopal disaster, which is also referred to as Bhopal gas tragedy, was a gas leak incident on the...

Q: Name the afferent process of a neuron.

A: The nervous system consists of neural tissues. Neurons, also known as nerve cells are the fundamenta...

Q: Natural selection changes allele frequenciesbecause some _________ survive and reproducebetter than ...

A:   Evolution is a natural process that includes several changes over many generations in the characte...

Q: Vitamin C is an organic molecule that helps many enzymes in the body function. A lack of vitamin C i...

A: Vitamin C is also known as ascorbic acid.It is used to prevent and treat scurvy. It is an essential ...

Q: What is cyclosporin? How are fungi related to this substance?

A: Immunosuppressive drugs are drugs that inhibit or prevent activity of the immune system. Immunosuppr...

Q: Hemophilia is a genetic disorder that compromises an individuals ability to form red blood cells  tr...

A: Haemophilia is one of the mostly inherited genetic disorders that impair the body's ability to make ...

Q: Generally YAC contains how many elements?a) 1b) 2c) 3d) 4

A: YAC stands for yeast artificial chromosomes and is widely used in the field of genetic engineering. ...

Q: The lumbar region is ________.a. inferior to the gluteal regionb. inferior to the umbilical regionc....

A: Lumbar in tetrapod anatomy refers to an adjective, which means of or relating to the abdominal secti...

Q: How are bacteria classifiedaccording to their need foroxygen?

A: The bacteria belong to the large class of prokaryotic micro-organisms. They are divided into various...

Q: What do you mean by nucleolus?

A: Cell, the unit of life, is composed of various organelles, which play vital role in the functioning ...

Q: What is the function of Permease?

A: Step 1 Lac operon of Escherichia coli has three structural genes, LacZ, LacY, and Lac A. In the indu...

Q: How was the concluded that gene are located on chromosomes?

A: Gene along with the histone protein forms the chromatin that eventually results in the formation of ...

Q: Name criterion, which is not indicate hypoparathyroidism:                                  A. Hyperc...

A: Hypoparathyroidism is a condition characterized by abnormally low levels of parathyroid hormone secr...

Q: What happens when an individual receives a transfusion with an incompatible blood type?

A: The blood is a fluid connective tissue formed of liquid portion plasma, and the solid portion called...

Q: Discuss the use of reverse transcriptase in the construction of a cDNA library?

A: Reverse transcriptase enzyme is naturally present in retroviruses (RNA type virus) to duplicate and ...

Q: Among the most prevalent pathologies that afflicthuman beings is heart disease, which can have a sev...

A: Heart diseases are chronic diseases that usually progress with age. The expression of genes is affec...