Evolutionary Analysis (5th Edition)
5th Edition
ISBN: 9780321616678
Author: Jon C. Herron, Scott Freeman
Publisher: PEARSON
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Chapter 1, Problem 3Q
Summary Introduction
To determine: The reason how some patients were infected with AZT-resistant strains of HIV-1 though they never received AZT.
Introduction: Acquired immunodeficiency syndrome (AIDS) is a life-threatening disorder that is caused by a retrovirus called human immunodeficiency virus (HIV). This is a life-threatening syndrome because the virus interferes with the body’s ability to fight against diseases by destroying T cells of the immune system.
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Chapter 1 Solutions
Evolutionary Analysis (5th Edition)
Ch. 1 - Prob. 1QCh. 1 - Prob. 2QCh. 1 - Prob. 3QCh. 1 - Given the risk of evolution of resistance, why do...Ch. 1 - Prob. 5QCh. 1 - Prob. 6QCh. 1 - In a monograph published in 1883, Alexander Graham...Ch. 1 - Design a study to test our prediction that human...Ch. 1 - Prob. 9QCh. 1 - Suppose that HIV were the ancestor of the SIVs,...
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- Which of the following is the most likely explanation for an individual who lacks CCR5 as a result of a homozygous defect in the CCR5 gene becoming infected with HIV? a. The mutated CCR5 genes reverted to the normal form, rendering macrophages susceptible to macrophagetropic HIV variants. b. The macrophage-tropic HIV variant entered host cells using CD4 alone. c. The viral nucleic acid alone was taken up by cells, as in cell transformation by bacterial DNA. d. The individual had received a transplant of HIV-infected cells expressing normal CCR5. e. The primary infection involved a lymphocyte-tropic strain of HIV that used CXCR4 as its co-receptor.arrow_forwardVaccines have effectively prevented many viral diseases. Attempts over many years to develop an effective vaccine against HIV disease and AIDS, however, have so far met with little success. Why is this so?arrow_forwardOne of the first and most important targets for drugs to fight infection with HIV (a retrovirus) is the reverse transcriptase enzyme. Why?arrow_forward
- Please help explain this LAPTM5 restricts HIV-1 and Vpr counteracts the restrictionarrow_forwardAccording to the article which was written before the COVID-19 vaccine was created, when do people turn to magic? How can this tendency, which happens across cultures and throughout history, contribute to the current spread of the novel coronavirus and its variants?arrow_forwardHow is AZT a competitive inhibitor of HIV reverse transcriptase?arrow_forward
- is HIV in humans different than HIV in rabbits? or the same.arrow_forwardHow is human immunodeficiency virus (HIV) resistant to disinfectants and antiseptics?arrow_forwardEfforts to produce an HIV vaccine have met with limited success. What aspects of the virus and its replicative strategy make it difficult to produce a vaccine against HIV? What other kind of virus might be similarly different to vaccinate against? What similarities and differences exist between the two types of virus that account for the differences in vaccine production?arrow_forward
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