Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 10, Problem 17RQ
What is the main prerequisite for clearance at the G2 checkpoint?
- cell has reached a sufficient size
- an adequate stockpile of
nucleotides - accurate and complete
DNA replication - proper attachment of mitotic spindle fibers to kinetochores
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During the cell cycle there are three checkpoints. Match each description with the correct checkpoint.
Requires growth signals and checks there are no mutation in the DNA
Checks that DNA is properly replicated and that all the organelles and proteins needed for division are present
Ensures that all the chromosomes are lined up and accounted for
A.
G1/S
B.
S/G2
C.
G2/M
D.
Metaphase/Anaphase
E.
Anaphase/Telophase
Cell cycle checkpoints are “quality checks” that pause the cell cycle to determine if it should proceed. If the DNA replication of the cell does not go well, and the DNA is damaged, this will be most likely detected at the..
G1 checkpoint
G2 checkpoint
M checkpoint
All of the above
Which of the following is NOT a checkpoint that controls the progression of cell cycle?
The metaphase checkpoint determines if all chromosomes are attached to the spindle apparatus
Cytokinesis involves the formation of cleavage furrow to separate the cells
The G2 checkpoint checks for DNA damage and determines if all of the DNA is replicated
Cyclins and cyclin dependent kinases are protejns that are responsible for advancing a cell through the phases of the cell cycle
Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
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- What is necessary for a cell to pass the G2 checkpoint? a. cell has reached a sufficient size b. an adequate stockpile of nucleotides c. accurate and complete DNA replication d. proper attachment of mitotic spindle fibers to kinetochoresarrow_forwardThe mitotic spindles arise from which cell structure? centromere centroscme kinetochore cleavage furrowarrow_forwardChromosomes are duplicated during what portion of the cell cycle? a. G 1 phase b. S phase c. prophase d. prometaphasearrow_forward
- Apoptosis can occur in a cell when the cell is damaged no longer needed infected by a virus all of the abovearrow_forwardNeurons are arrested in ________ of the cell cycle. a. G1 b. anaphase c. prophase d. S phasearrow_forwardAfter mitosis, each daughter cell contains genetic instructions that are ______ and _____ chromosome number of the parent cell. a. identical to the parent cells; the same b. identical to the parent cells; one-half the c. rearranged; the same d. rearranged; one-half thearrow_forward
- The chromosomes become visible under a light microscope during which stage of mitosis? prophase prometaphase metaphase anaphasearrow_forwardDuring interphase of the cell cycle, the chromosomes (DNA mass) of a cell _________. decreases during S phase increases (doubles) during the S phase Increases during M phase decreases during G1arrow_forwardWhich negative regulatory molecule can trigger cell suicide (apoptosis) if vital cell cycle events do not occur? a. p53 b. p21 c. retinoblastoma protein (Rb) d. cyclin-dependent kinase (Cdk)arrow_forward
- A drawing of a cell in anaphase is provided. The cell contains 8 unreplicated chromosomes with alleles (H, h, F, f) properly labeled. The chromosomes are shown separating from each other with 4 chromosomes moving toward each side of the cell. Spindle fibers are labeled.arrow_forwardWhat is a role of cyclines in regulating the cell cycle? Describe the significance of checkpoints monitoring proteins check for aberrant cell cycle events.arrow_forwardWhat happens during the S phase of the cell cycle? The cell divides The cell undergoes its final preparation for division The cell undergoes its initial growth phase The cell replicates its DNAarrow_forward
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