Microbiology with Diseases by Taxonomy (5th Edition)
Microbiology with Diseases by Taxonomy (5th Edition)
5th Edition
ISBN: 9780134019192
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 10, Problem 1MC
Summary Introduction

Introduction:

To devise an effective treatment for the infectious disease, the determination of antimicrobial agent which is most effective against a specific pathogen is necessary. Various tests are there to test the effectiveness of antimicrobials like minimum inhibitory concentration test, diffusion susceptibility tests, and minimum bactericidal test.

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Answer to Problem 1MC

Correct answer:

Diffusion and dilution tests which expose the pathogens to antimicrobials are designed to determine “which drug is most effective against a particular pathogen and the amount of a drug to use against a particular pathogen”.

Therefore, option (d) is correct.

Option (d) is given as “both b and c”.

Explanation of Solution

Justify the reason for the correct statement:

The tests like diffusion and dilution expose disease-causing pathogens to antimicrobials to determine the amount and effectiveness of antimicrobial test to use against a specific pathogen.

Hence, option (d) is correct.

Justify the reasons for the incorrect statements:

Option (a) is given as “the spectrum of action of a drug”.

Diffusion and dilution tests do not determine the spectrum range of an antimicrobial drug. Hence, it is a wrong answer.

Option (b) is given as “which drug is most effective against a particular pathogen”.

Diffusion and dilution tests determine the effectiveness of a particular drug against a particular pathogen. But these tests also determine the amount of drug which is effective against a particular pathogen. Hence, it is a wrong answer.

Option (c) is given as “none of the above would best represent a population growth curve”.

Diffusion and dilution tests determine the amount of drug which is effective against a particular pathogen. But these tests also determine the effectiveness of a particular drug against a particular pathogen. Hence, it is a wrong answer.

Hence, options (a), (b), and (c) are incorrect.

Conclusion

Tests like diffusion and dilution tests are used to determine both the effectiveness and amount of drug against a particular pathogen.

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Which of the following is not a property of an antimicrobialagent?(a) Must have a favorable chemotherapeutic index(b) Must be selectively toxic(c) Must be effective against viral diseases(d) Must have a known concentration over a period oftime required to eliminate a pathogen(e) b and c
A factor in the zone of inhibition size on the Kirby-Bauer plate is: a. amount of medium placed on the plate b. rate of diffusion of the drug used c. stage of growth of the microbe placed on the plate d. all of these
Which of the following is NOT a property of an antimicrobial agent? a. Must have a known concentration over a period of time required to eliminate a pathogen b. all choices are correct c. must be selectively toxic d. Must have a favorable chemotherapeutic index

Chapter 10 Solutions

Microbiology with Diseases by Taxonomy (5th Edition)

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