Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 10, Problem 32CTQ
Chemotherapy drugs such as vincristine (derived from Madagascar periwinkle plants) and colchicine (derived from autumn crocus plants) disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Exactly what mitotic structure is targeted by these drugs and what effect would that have on cell division?
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Chemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Explicitly referring to Mitosis, explain what mitotic structure is targeted by these drugs, and what effect would this have on cell division?
The drug chloral hydrate prevents elongation of microtubules by preventing the addition of new subunits to the growing end. During which stage of mitosis would chloral hydrate be most harmful?
Which stage of the cell cycle is the longest?
Why are onion root tips a good choice for viewing cells in different stages of the cell cycle?
Are there any mammalian cells that would be a good source for dividing cells? What types of cells would most like NOT have cells undergoing division?
Chapter 10 Solutions
Biology 2e
Ch. 10 - Figure 10.6 Which of the following is the correct...Ch. 10 - Figure 10.13 Rb and other proteins that negatively...Ch. 10 - Figure 10.14 Human papillomavirus can cause...Ch. 10 - A diploid cell has ________ the number of...Ch. 10 - An organism s traits are determined by the...Ch. 10 - The first level of DNA organization in a...Ch. 10 - Identical copies of chromatin held together by...Ch. 10 - S. Chromosomes are duplicated during what stage of...Ch. 10 - Which of the following events does not occur...Ch. 10 - The mitotic spindles arise from which cell...
Ch. 10 - Attachment of the mitotic spindle fibers to the...Ch. 10 - Unpacking of chromosomes and the formation of a...Ch. 10 - Separation of the sister chromatids is a...Ch. 10 - The chromosomes become visible under a light...Ch. 10 - The fusing of Golgi vesicles at the metaplhase...Ch. 10 - At which of the cell-cycle checkpoints do external...Ch. 10 - What is the main prerequisite for clearance at the...Ch. 10 - If the M checkpoint is not cleared, what stage of...Ch. 10 - Which protein is a positive regulator that...Ch. 10 - Many of the negative regulator proteins of the...Ch. 10 - Which negative regulatory molecule can trigger...Ch. 10 - are changes to the order of nucleotides in a...Ch. 10 - A gene that codes for a positive cell-cycle...Ch. 10 - A mutated gene that codes for an altered version...Ch. 10 - Which molecule is a Cdk inhibitor that is...Ch. 10 - Which eukaryotic cell-cycle event is missing in...Ch. 10 - FtsZ proteins direct the formation of a...Ch. 10 - Compare and contrast a human somatic cell to a...Ch. 10 - What is the relationship between a genome,...Ch. 10 - Eukaryotic chromosomes are thousands of times...Ch. 10 - Briefly describe the events that occur in each...Ch. 10 - Chemotherapy drugs such as vincristine (derived...Ch. 10 - Describe the similarities and differences between...Ch. 10 - List some reasons why a cell that has just...Ch. 10 - What cell-cycle events will be affected in a cell...Ch. 10 - Describe the general conditions that must be met...Ch. 10 - Compare and contrast the roles of the positive...Ch. 10 - What steps are necessary for Cdk to become fully...Ch. 10 - Rb is a negative regulator that blocks the cell...Ch. 10 - Outline the steps that lead to a cell becoming...Ch. 10 - Explain the difference between a proto-oncogene...Ch. 10 - List the regulatory mechanisms that might be lost...Ch. 10 - ______ can trigger apoptosis if certain cell-cycle...Ch. 10 - Name the common components of eukaryotic cell...Ch. 10 - Describe how the duplicated bacterial chromosomes...
Additional Science Textbook Solutions
Find more solutions based on key concepts
Ina traction setup a broken bone, with pulleys and rope available, how might we be able to Increase the force a...
College Physics
QUANTITATIVE Punnett Squares as Genetic Tools. The genetic characters of seed color (where Y is the allele for ...
Becker's World of the Cell (9th Edition)
Fibrous connective tissue consists of ground substance and fibers that provide strength, support, and flexibili...
Human Biology: Concepts and Current Issues (8th Edition)
1. ___ Mitosis 2. ___ Meiosis 3. __ Homologous chromosomes 4. __ Crossing over 5. __ Cytokinesis A. Cytoplasmic...
Microbiology with Diseases by Body System (4th Edition)
21-Year-Old Female with Skeletal Injuries
While riding her bike to campus, 21-year-old Liliana Rose was struck...
Human Anatomy & Physiology (11th Edition)
Some organizations are starting to envision a sustainable societyone in which each generation inherits sufficie...
Campbell Essential Biology (7th Edition)
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The individual chromosomes become visible with a light microscope during which stage of mitosis? a. prophase b. prometaphase c. metaphase d. anaphasearrow_forwardAll of the following are stages of mitosis except _________. a. prophase b. interphase c. metaphase d. anaphasearrow_forwardBiologists have long been interested in the effects of radiation on cells. In one experiment, researchers examined the effect of radium on mitosis of chick embryo cells growing in culture. A population of experimental cells was examined under the microscope for the number of cells in telophase (as a measure of mitosis occurring) before, during, and after exposure to radium. The results are shown in the Figure. What is the effect of radium exposure on mitosis? Source: R. G. Canti and M. Donaldson. 1926. The effect of radium on mitosis in vitro. Proceedings of the Royal Society of London, Series B, Containing Papers of a Biological Character 100:413419.arrow_forward
- Speculate on how the Hayflick limit may lead to genetic disorders such as progeria and Werner syndrome. How is this related to cell division?arrow_forwardChromosomes are duplicated during what portion of the cell cycle? a. G 1 phase b. S phase c. prophase d. prometaphasearrow_forwardThe image below is of a stained onion root tip. Determine the phase of mitosis that each cell below is in, and record that below. Look closely - cells that are clearly stained are numbered in the image below. Use those numbers when assigning the phase of mitosis for each cell. Using the same onion root tip image and data from the question above, which phase are the majority of cells in? Make a conclusion about what this means about the length of each phase of the cell cycle.arrow_forward
- The cell cycle is highly regulated and involves many steps to ensure that a cell is ready to divide. For this reason, cells cycle between interphase and mitosis. Which of the following describes the consequence of a severe disruption of interphase in cells in healthy tissue? Disruption of interphase will have no effect on mitosis because they are two completely independent processes. Disruption of interphase will lead to a faster and more efficient mitotic cycle, which will result in increased cell division and tissue growth. Disruption of interphase will trigger the cell to switch to a mitotic phase and repeatedly divide, which will result in the massive proliferation of the cells and heightened tissue growth. Disruption of interphase will result in the cell being unable to synthesize proteins and organelles required to divide, which will result in the cell not passing key checkpoints and ceasing to divide.arrow_forwardWhat is the name of the cytoplasm division in the end of mitosis? What are the differences in this process between animal and plant cells?arrow_forwardmany anticancer drugs inhibit the formation of the mitotic spindle. what inpact will this have on cell division? why?arrow_forward
- In which two phases of mitosis would you find a nuclear membrane (or at least fragments of it)? Group of answer choices A. prophase & telophase B. prophase & anaphase C. telophase & anaphase D. prophase & metaphase E. metaphase & anaphasearrow_forwardWhat is the final result of mitosis in a human A) nearly genetically identical 2n somatic cells B) genetically different 2n somatic cells C) nearly genetically identical 1n somatic cells D) genetically identical 2n gamete cells Which of the following statements is TRUE? A) A single, replicated chromosome with sister chromatids has two centromeres. B) A single, unreplicated chromosome has two DNA molecules. C) Sister chromatids from a single chromosome are connected at the centromere. D) Homologous chromosomes are connected at the centromere. The first gap in the cell cycle (G1) corresponds to _____. A) normal growth and cell function B) the phase in which DNA is being replicated C) the beginning of mitosis D) the phase between DNA replication and the M phase In a diploid cell from a specific species has 5 chromosome pairs, how many sister chromatids will be found in a nucleus at prophase of mitosis? (Draw it!) A) 5 B) 10 C) 20 D) 40 Consider a cell from the species above.…arrow_forwardIn regards to MITOSIS, give the order of the following events in terms of chromosome number. Question 7 options: one cell containing 92 chromosomes mitosis & cytokinesis one cell containing 46 chromosomes two cells containing 46 chromosomesarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning 
Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Biology Today and Tomorrow without Physiology (Mi...
Biology
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cengage Learning
The Cell Cycle and its Regulation; Author: Professor Dave Explains;https://www.youtube.com/watch?v=eqJqhA8HSJ0;License: Standard YouTube License, CC-BY
Cell Division - Mitosis and Meiosis - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=w7vp_uRA8kw;License: Standard YouTube License, CC-BY