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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 10.4, Problem 1GR
Textbook Problem
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The amino acid tyrosine is synthesized from phenylalanine. Does this make tyrosine an essential amino acid in individuals with PKU?

Summary Introduction

To explain:  Whether the amino acid tyrosine is an essential amino acid in individuals suffering with PKU..

Introduction: Phenylketonuria (PKU) is a genetic disorder that is inherited from one generation into the next. PKU is caused because of the mutation in the gene that codes for the enzyme required for metabolism of phenylalanine. This mutation causes synthesis of the defective enzyme and thus, proper metabolism of phenylalanine is not achieved.

Explanation of Solution

Phenylketonuria, a genetic disorder, is inherited from parents to their offsprings. This disease causes synthesis of a defective enzyme which affects phenylalanine metabolism. Phenylalanine metabolism is essential for the synthesis of tyrosine which is a non-essential amino acid in a healthy individual.

Amino acids that are synthesized in the body itself are called non-essential amino acids, such as serine, alanine, arginine, tyrosine and many more. Amino acids that are required to be taken from diet are called essential amino acids, such as valine, leucine, isoleucine, methionine, and many more...

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