Interpretation:Purpose of usage of the ethereal solution to rinse and wash the product with bicarbonate solution as well as with saturated brine should be determined.
Concept introduction:Ethereal solution refers to the organic layer. After the synthesis, the key step is to work up that involves the isolation of the pure desired product. This may require some rinse with solvents that depend upon the nature of impurities.
If the impurities are acidic the basic solution is suggested while for basic impurities aqueous hydrochloric acid may be used up for dissolution and removal of any basic impurities. For impurities that are polar such as traces of moisture the brine solution that is also polar and of similar nature is an appropriate solvent.
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EBK EXPERIMENTAL ORGANIC CHEMISTRY: A M
- Complete these reactions involving lithium diorganocopper (Gilman) reagents. (a) (b) (c) (d)arrow_forwardWhy should the purified compound at the well (Buchner funnel) not be washed with a larger amount of pure solvent?arrow_forwardWhy is it necessary to store the prepared lysates in a very low temperature?arrow_forward
- How can the Eugenol content be separated from the alkaline solution?arrow_forwardQ1: Give one lysis buffer that is commonly used for western blotting experiments and include its components Q3: To make sure that you used a similar amount of samples, what important step should be done before proceeding the electrophoresis stage? Q4. Why is it necessary to store the prepared lysates in a very low temperature?arrow_forwardA Grignard reaction of phenylmagnesium bromide with 3-pentanone gives 3-phenylpentan-3-ol as the major product. The crude product contains the 3-phenylpentan-3-ol product, unreacted 3-pentanone, and biphenyl (a side product). A developing solvent is found that separates the mixture into three spots on a silica gel TLC plate. Considering the functional groups present, predict which compounds would have the smallest and largest Rf values. Briefly justify your answer.arrow_forward
- What is the chemical composition of the nitrating mixture? Why does the incoming nitro group go para and not ortho?arrow_forwardWhy is diethyl ether used as a solvent for the reduction reaction of the keystone (3,3-dimethyl-2-butanone) utilizing the reducing agent sodium borohydride (NaBH4). what is the purpose of was repeated washes with water? What is the purpose of repeated washes with brine?arrow_forwardWhat indication in the "test tube test" (procedural step 9) will be given if Na3PO4 is the limiting reagent? What if BaCl2 is the limiting reagent? Explain whyarrow_forward
- Why is it necessary to exclude moisture in the Grignard reaction? Be specific. What happens to the phenylmagnesium bromide if trace water is present? What compound is formed?arrow_forwardCompare the solubilities of Bis(pyridine)iodine nitrate in chloroform and in ether.arrow_forwardIdentify The resulting color of the solution upon the addition of dilute sodium hydroxide in phthalein dye testarrow_forward
- EBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENTOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning