Interpretation:
Common role of the Chromium containing group, periodinane, and the dimethyl sulfide of the given reaction has to be discussed.
Concept Introduction:
Oxidation of alcohols: Oxidation of primary alcohol gives an
Leaving group: Leaving group can be any groups or atoms that get detached from either neutral or charged organic compounds. The stability of the leaving group is to stabilize the electron density that results from heterolysis cleavage of bond.
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OWLv2 with MindTap Reader, 1 term (6 months) Printed Access Card for Brown/Iverson/Anslyn/Foote's Organic Chemistry, 8th Edition
- 8,9,10arrow_forwardWhy is a strong acid (like HCI) used in a Grignard reaction? O 1) A strong acid is used in the Grignar reaction in order to protonate the carbonyl in order to make a better leaving group, OH. Once teh OH leaves, the alcohol group is reformed due to water. A stable tetrahedral intermediate with a negatively charged oxygen forms O 2) that does not possess a leaving group. This intermediate will exist until a proton source from the strong acid protonates the negatively charged oxygen, affording the neutral alcohol product. 3) The use of a strong acid is not necessary. It is simply recommended as it increases the yield produced in the reaction. 4) The use of a strong acid is necessary for the formation of a Grignard reagent. Without a strong acid, the organomagnesium compound cannot be formed.arrow_forwardIn each reaction box, place the best reagent and conditions from the list. 1) CEN 2) 3) 4) 5) Answer Bank NANH, NaBH, acetone CH,CH, MgBr (excess) acetic acid acetate ion CH,OH, H,O* (cat.) LIAIH, (CH,),CHMgBr (excess) CH,MgBr (excess) H,0 H,0*, H,0, heat acetyl chloridearrow_forward
- Which of the following parameters affects the rate and kinetics of a reaction? A. Solvent medium B. Reaction temperature C. Reaction time D. Geometry and structure of the alkyl halide E. pHarrow_forwardWhich of the following reagents will not undergo a substitution reaction with the benzenediazonium chloride salt. A. H3PO2 , H2O B. H3PO3, H2O C. Cu2O, Cu+2, H2O D. KI E.CuCNarrow_forwardDepending on the structure of the organic halide, one or both of these methods may be employed. Complete the following reaction scheme. Part 1- For the given organic halide, select the method(s) that provide the appropriate reagents for steps 1 and 2. Select the single best answer. A. Method 1 only B. Method 2 only C. Both methods 1 and 2arrow_forward
- Which of the following reagents will not undergo a substitution reaction with the benzenediazonium chloride salt. A. H3PO3, H2O B. CuCN C. Cu2O, Cu+2, H2O D. H3PO2 , H2O E. KIarrow_forward10. Three atoms, A-C, are indicated in the structure below. To which atom is a nucleophile more likely to form a bond? Briefly explain your answer. Aarrow_forwardConsider the following reaction (at equilibrium), Flavylium cation +H2O + heat ↔ Hydrated flavylium + OH- (colored) (colorless) For the reaction above, which of the following is TRUE? a.None of the choices is correct. b.Placing the solution in cold ice bath will lead to discoloration. c.Adding HCl will lead to formation of more flavylium cation. d.Decreasing the pH of the solution will lead to a colorless solution.arrow_forward
- QUESTION 4 Which of the following are good nucleophiles and weak bases? Choose all that apply. O. HOC(CH3)3 II. CH3CH2SNa III. NacCCH3 O IV. KOCH2CH3 OV. CH3CH2NH2 O VI. CH3CO2Na O VII. LIN[CH(CH3)2)12arrow_forwardDraw the energy diagram of the following reaction. Label and draw the reactants, intermediates, and products. Label the transition state of the rate limiting step and draw the transition state of the rate determining step. Is it a concerted or stepwise reaction? Write the rate law for this reaction. How do we increase the reaction rate? If we use deutrium-tert-butyl bromide such as (CD3)3CBr instead of (CH3)3CBr, will it increase or decrease the reaction rate, or is there no meaningful rate change? Write reasons for your answer. Draw mechanisms for reactions by drawing arrows and intermediates.arrow_forward6. For the following reactions, predict the major and minor products. Label each. 1. BH₂/THF 2. H₂O₂, OH, H₂O 1. Hg(OAC)2, H₂O 2. NaBH₁arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningEBK A SMALL SCALE APPROACH TO ORGANIC LChemistryISBN:9781305446021Author:LampmanPublisher:CENGAGE LEARNING - CONSIGNMENT