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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 11, Problem 10QP
Textbook Problem
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If the coding region of a gene (the exons) contains 2,100 base pairs of DNA, would a missense mutation cause a protein to be shorter, longer, or the same length as the normal 700 amino acid proteins? What would be the effect of a nonsense mutation? A sense mutation?

Summary Introduction

To explain: The effect of a missense mutation on the gene containing 2,100 base pairs.

Introduction: Mutation is the change in the original nucleotide sequence of the DNA. During mutation, the nucleotide can be added, deleted, or transformed. A change in the structure of the chromosome also leads to mutation. It can be heritable or non-heritable. If a mutation occurs in somatic cells, it is non-heritable; while a mutation in germ cells is heritable and can affect generations. Mutation leads to different types of cancer.

Explanation of Solution

A missense mutation is a type of mutation in which there is a single nucleotide change in the sequence of DNA. Due to the nucleotide change, one amino acid is substituted by another amino acid...

Summary Introduction

To explain: The effect of the nonsense mutation on the gene containing 2,100 base pairs.

Introduction: Mutation is the change in the original nucleotide sequence of the DNA. During mutation, the nucleotide can be added, deleted, or transformed. A change in the structure of the chromosome also leads to mutation. It can be heritable or non-heritable. If a mutation occurs in somatic cells, it is non-heritable; while a mutation in germ cells is heritable and can affect generations. Mutation leads to different types of cancer.

Summary Introduction

To explain: The effect of sense mutation on the gene containing 2,100 base pairs.

Introduction: Mutation is the change in the original nucleotide sequence of the DNA. During mutation, the nucleotide can be added, deleted, or transformed. A change in the structure of the chromosome also leads to mutation. It can be heritable or non-heritable. If a mutation occurs in somatic cells, it is non-heritable; while a mutation in germ cells is heritable and can affect generations. Mutation leads to different types of cancer.

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