Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 11, Problem 14QP
In the gene-coding sequence shown here, which of the following events will produce a frameshift after the last mutational site?
- a. insertion of an A after the first codon
- b. deletion of the second codon (AAA)
- c. insertion of TA after the second codon and deletion of CG in the fourth codon
- d. deletion of AC in the third codon
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Students have asked these similar questions
Which of the following mutations is likely to be the least harmful?
A. A +1 frameshift mutation
B. A +3 frameshift mutation
C. A - 5 frameshift mutation
D. A -1 frameshift mutation
E. A point mutation in the first position of the codon
Finally, imagine that a mutation occurred in the codon below and an A was inserted between the two Ts. How would this affect the mRNA and the amino acid for that codon?
Old DNA codon
Old RNA codon
Old amino acid
New DNA codon
New mRNA codon
New amino acid
T T G
T A T G
This would be an example of which type of a mutation?__________________________
If you imagine a messenger RNA molecule in the cytoplasm of a cell, which of the following will likely affect how much protein is made by translation of this message?
A. The presence of appropriate snRNPs.
B. The length of the polyA tail.
C. The strength of hydrogen bonds holding the mRNA to ribosomal RNA.
D. The ability of the mRNA to pair with itself to form a helix-turn-helix structure.
Chapter 11 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 11.4 - Consumer products including bandages, cotton...Ch. 11.4 - Prob. 2EGCh. 11 - Prob. 1CSCh. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 - Prob. 1QPCh. 11 - Achondroplasia is an autosomal dominant form of...Ch. 11 - Why is it almost impossible to directly measure...Ch. 11 - What are the factors that influence the mutation...Ch. 11 - Achondroplasia is a rare dominant autosomal defect...
Ch. 11 - Although it is well known that X-rays cause...Ch. 11 - Prob. 7QPCh. 11 - Bruce Ames and his colleagues have pointed out...Ch. 11 - Define and compare the following types of...Ch. 11 - If the coding region of a gene (the exons)...Ch. 11 - Two types of mutations discussed in this chapter...Ch. 11 - Prob. 12QPCh. 11 - A frameshift mutation is caused by a: a....Ch. 11 - In the gene-coding sequence shown here, which of...Ch. 11 - Prob. 15QPCh. 11 - Familial retinoblastoma, a rare autosomal dominant...Ch. 11 - Tay-Sachs disease is an autosomal recessive...Ch. 11 - Replication involves a period of time during which...Ch. 11 - Our bodies are not defenseless against mutagens...Ch. 11 - The cystic fibrosis gene encodes a chloride...
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- Imagine that a mutation in a DNA molecule results in the codon CCU being changed to CCC. Both of these codons code for proline. The fact that more than one codon can code for the same amino acid is referred to as ___ a. the ambiguity of the genetic code b. the redundancy of the genetic code c. the randomness of the genetic code d. mutations in the genetic codearrow_forwardHow do we call the type of point mutation in which an A->U change occurs in the codon for the sixth amino acid in hemoglobin chain b? a) Inversion b) Transversion c) Transition d) Transaminationarrow_forwardWhich of the following would probably cause the most severe damage to a gene's expression and phenotype a. A missense mutation changing the first methionine codon to an arginine codon. b. A deletion of a base in the 455th codon of a 456-amino acid protein. c. Alteration of a UGG codon to a UGA codon at position 324 of a 324 amino acid protein. d. Mutation of a GUC codon (valine) to a GUU codon (valine).arrow_forward
- 1. Translation a)Explain the role of ribosomes in the process of protein translation.b. Explain the role of tRNA molecules in protein translation.c. Define the following terms:1. codon 2. anticodon. Explain how a codon is used in the process of translation.arrow_forwardThe change of a UAC codon (Tyr) to a UAU codon (Tyr) is an example of a: A. missense mutation B. silent mutation C. frameshift mutation D. nonsense mutationarrow_forwardWhich of the following best describes tRNA? a. Provides the instructions for the amino acid sequence of a polypeptide b. Complexes with ribosomal proteins to form ribosomes c. Used for eukaryotic RNA processing d. Transports amino acids to ribosomes during translationarrow_forward
- A particular tRNA is mutated so that the amino acid attachment cannot bind with the aminoacyl-tRNA synthase. What happens when an mRNA transcript contains the codon for this tRNA? A. The tRNA will not bind to this codon. B. Translation stops and the protein is released. C The wrong tRNA is added to the protein chain. D. Translation stops and the protein remains bound to the ribosome.arrow_forwardWhich of the following mutations would be most likely to havea harmful effect on an organism?(A) a deletion of three nucleotides near the middle of a gene(B) a single nucleotide deletion in the middle of an intron(C) a single nucleotide deletion near the end of the codingsequence(D) a single nucleotide insertion downstream of, and close to,the start of the coding sequencearrow_forwardWhich of the following regions on the tRNA are composed of a sequence of nucleotides? a. anticodon that binds to codon in mRNA b. anticodon that binds to codon in ribosomes c. anticodon that binds to codon in tRNA synthetase d. none of the abovearrow_forward
- Which of the following describes the interactions between a codon and an anticodon? A. A codon and an anticodon become covalently bonded together due to the activity of the ribosome. B. A codon and anticodon do not come into direct contact because codons are in the nucleus but anticodons are in the cytoplasm. C. A codon and anticodon are attracted to each other due to hydrogen bonding. D. A codon and an anticodon are linked together by an amino acid. ..arrow_forwardAminoacyl-tRNA is a key player in the translation process. Which of the following is the ONE component of this molecule that is unique? A. the codon B. the anticodon C. the amino acid D. the amino acid attachment sitearrow_forward_______ are removed from new mRNAs. a. Introns c. Poly-A tails b. Exons d. Amino acidsarrow_forward
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