The reason behind the father not developing retinoblastoma. Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

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Answer 1

Question

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

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Students have asked these similar questions

A couple has one child with bilateral retinoblastoma. The mother is free from cancer, but the father has unilateral retinoblastoma and he has a brother who has bilateral retinoblastoma. a. If the couple has another child, what is the probability that this next child will have retinoblastoma? b. If the next child has retinoblastoma, is it likely to be bilateral or unilateral? c. Explain why the father’s case of retinoblastoma is unilateral, whereas his son’s and brother’s cases are bilateral.

How can the retinoblastoma trait be inherited in a dominant fashion if the deletion of the RB gene is recessive to the wild-type RB+ allele?

Do you think a patient needs to have the SAME two mutant alleles of CFTR to present with/have cystic fibrosis? Why or why not?

Answer 2

Question

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

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Answer 3

Question

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

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Answer 4

Question

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

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Answer 5

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

Answer 6

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

Answer 7

Chapter 12, Problem 12QP

a.

Summary Introduction

To determine: The reason behind the father not developing retinoblastoma.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main cause of this condition is due to the mutation in cells. These mutations affect the contact inhibition amongst cells. Retinoblastoma is cancer of eyes in which the retinoblast cells grow uncontrollably.

Answer 8

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

Answer 9

b.

Summary Introduction

To determine: The chance that the couple will have another child carrying the mutant allele.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in the RB1 gene. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

Answer 10

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

Answer 11

c.

Summary Introduction

To determine: Whether there a benefit to knowing that the son in the given case may develop retinoblastoma.

Introduction: The hereditary form of cancer is responsible for bilateral retinoblastoma. Bilateral retinoblastoma is caused due to a mutation in both the RB1 genes in a person. This type of cancer occurs due to a mutation in the tumor-suppressing gene and the homozygous condition is required for cancer to occur

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 12.10 - If improved diagnostic tests are developed from...Ch. 12.10 - If you had cancer, would you donate tissue samples...Ch. 12.10 - Prob. 1GR Ch. 12.10 - Another model, the random model, proposes that any...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Mike was referred for genetic counseling because...Ch. 12 - Theodor Boveri predicted that malignancies would...Ch. 12 - Distinguish between a familial and a sporadic...Ch. 12 - Benign tumors: a. are noncancerous growths that do...

Solution Summary: The author explains that the hereditary form of cancer is responsible for bilateral retinoblastoma.

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