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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12, Problem 19QP
Textbook Problem
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Explain how the APC gene starts the progress toward colon cancer.

Summary Introduction

To explain:  The role of the APC gene in the progression of colon cancer.

Introduction: Colon cancer is defined as the uncontrolled growth of cells of the large intestine, specifically colon, which is the end region of the large intestine. Mostly, colon cancer is benign by nature, but in some cases, it can be malignant as well. The cancer property is shown by adenomatous polyps that are non-cancerous tumors, present in the large intestine.

Explanation of Solution

APC stands for Adenomatous Polyposis Coli. This gene is responsible for the translation of the APC protein which is necessary for controlling the beta-catenine concentration. Mutation in the APC gene results in the development of a benign tumor, and this cancer is known as familial adenomatous polyposis...

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