menu
bartleby
search
close search
Hit Return to see all results
close solutoin list

In Section 12-1, Julie is concerned that she may develop breast cancer, but testing shows that she does not carry the rare high-risk BRCA1 and BRCA2 alleles. What if further testing showed that some of her aunts, her mother, and she carried a common low-risk allele for breast cancer. What would you recommend to Julie if you were her genetic counselor?

BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

Solutions

Chapter
Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12, Problem 22QP
Textbook Problem
1 views

In Section 12-1, Julie is concerned that she may develop breast cancer, but testing shows that she does not carry the rare high-risk BRCA1 and BRCA2 alleles. What if further testing showed that some of her aunts, her mother, and she carried a common low-risk allele for breast cancer. What would you recommend to Julie if you were her genetic counselor?

Summary Introduction

To explain: The chances of developing breast cancer if both the high-risk BRCA1 and BRCA2 alleles are absent but Julie and her aunt and mother carried a common low-risk allele for breast cancer.

Introduction: BRCA1 acts as a mediator of the DNA repair mechanism. BRCA1 is a tumor-suppressing gene BRCA1 along with BRCA2 is involved in three important parts of cell division namely; DNA repair, DNA damage-induced cell cycle checkpoint activation, and apoptosis.

Explanation of Solution

Both the mother and the aunts of Julie carry a low-risk allele for cancer, so it is highly probable that Julie has also inherited these genes from her mother...

Summary Introduction

To determine: The recommendations that should be given to Julie by her genetic counselor.

Introduction: Cancer is not a result of single mutation but instead, it occurs due to the accumulation of the mutations. These mutations alter the structure of the proteins; thereby, making the protein nonfunctional or over expressive. This property of the proteins causes repeated divisions of the cells and makes the cells cancerous.

Still sussing out bartleby?

Check out a sample textbook solution.

See a sample solution

The Solution to Your Study Problems

Bartleby provides explanations to thousands of textbook problems written by our experts, many with advanced degrees!

Get Started

Chapter 12 Solutions

Human Heredity: Principles and Issues (MindTap Course List)
Show all chapter solutions
add

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions add
True or false? All hormones secreted by arthropods are also secreted by vertebrates.

Biology: The Unity and Diversity of Life (MindTap Course List)

All of the following are potential benefits of regular physical activity except improved body composition. lowe...

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

A 40.0-kg box initially at rest is pushed 5.00 m along a rough, horizontal floor with a constant applied horizo...

Physics for Scientists and Engineers, Technology Update (No access codes included)

Are there tides in the open ocean?

Oceanography: An Invitation To Marine Science, Loose-leaf Versin