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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12, Problem 7QP
Textbook Problem
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It is often the case that a predisposition to certain forms of cancer is inherited. An example is familial retinoblastoma. What does it mean to have inherited an increased probability of acquiring a certain form of cancer? What subsequent event(s) must occur?

Summary Introduction

To determine: The meaning of inheriting an increased probability of acquiring a certain form of cancer.

Introduction: Cancer is defined as the condition in which the cells start showing abnormal and uncontrolled growth. The main causes of this condition are mutations which affect the property of contact inhibition among different types of cells. The substances causing the mutation are called carcinogens. Genomic sequencing is the latest technique focused on studying different aspects of genes that contribute to cancer development and also different genetic mutations that can cause cancer.

Explanation of Solution

Cancer can occur due to mutation in the autosomes or in the germ cells. The autosomal form of cancer cannot be inherited but the mutations in the germ cells are inherited by the offsprings...

Summary Introduction

To determine: The subsequent event(s) that must occur after acquiring a certain form of cancer.

Introduction: Cancer genes are mostly present in the autosomes and are not inherited by a person. This type of cancer is called sporadic cancer and if the mutation occurs in the germ cells it can be inherited by the offspring and this type of cell is called familial cancer.

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Human Heredity: Principles and Issues (MindTap Course List)
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