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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 12.10, Problem 1GR
Textbook Problem
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Does the cancer stem cell hypothesis undercut the idea that cancers have a clonal origin, or can the two ideas be reconciled?

Summary Introduction

To determine:  If the cancer stem cell hypothesis undercut the idea that cancers have a clonal origin, or can these two ideas be reconciled.

Introduction: Stem cells are the undifferentiated mass of cells that continue to divide until specific signals lead to their differentiation. The differentiation results in the conversion of stem cells into a specific type of cells in a cell lineage. Cancer cells also show continuous division but these cells are differentiated cells and are harmful to the body.

Explanation of Solution

The stem cell hypothesis contradicts the random model of cancer development. According to the stem cell hypothesis, cancer cells follow two pathways of cell division. The first pathway causes rapid division for cell renewal and the second pathway c...

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