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Biochemistry

6th Edition
Reginald H. Garrett + 1 other
ISBN: 9781305577206

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BuyFindarrow_forward

Biochemistry

6th Edition
Reginald H. Garrett + 1 other
ISBN: 9781305577206
Textbook Problem

Answers to all problems are at the end of this book. Detailed solutions are available in the Student Solutions Manual, Study Guide, and Problems Book.

Examine the ActiveModel for glutamate-oxaloacetate aminotransferase (pdb id = GOT1) and identify the amino acid side chains involved in binding pyridoxal-5 '-phosphate

Interpretation Introduction

To propose:

The active model for glutamate-oxaloacetate aminotransferase (pdb id= GOT1) and identifying the amino acid side chains involved in binding pyridoxal-5’-phosphate.

Introduction:

The displacement bisubstrate transfers an amino group to transform a keto acid into amino acid.

Explanation

The keto acid is transferred into the amino acid by the transfer of an amino group by the double displacement bisubstrate mechanism. It also removes the same amino group for transformation of amino acid to a keto acid. Organisms use this transfer mechanism to change some amino acids from the environment into the amino acids which can be used for biological functions. Aminotransferase is the group of enzymes used for the catalyzation of this type of the mechanism. Pyridoxal-5’-phosphate creates the enzyme substrate complex that are reaction-favorable to facilitates the transfer...

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