Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 13, Problem 3TYK
Individuals affected by a condition known as polydactyly have extra fingers or toes. The following pedigree shows the pattern of inheritance of this trait in one family:
From the pedigree, can you tell if polydactyly comes from a dominant or recessive allele? Is the trait sex-linked? As far as you can determine, what is the genotype of each person in the pedigree with respect to the trait?
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The following pedigree shows the inheritance of Huntington’s disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington’s disease.
Using just the information on this pedigree, is Huntington’s disease caused by a dominant allele or recessive alleles?
What are the genotypes of the grandparents (I-1 and I-2)?
What are the genotypes of the parents (II-6 and II-7)?
If the parents above have another child, what is the chance that they will be affected by the Hungtington’s disease allele?
What are the genotypes of the unaffected children (III-8, 9, 10)?
What is the chance that the unaffected children above will pass on a Huntington’s disease allele to their children?
What is the genotype of the affected child (III-11)?
What is the chance…
For a recessive condition, two normal heterozygous individuals have children.
What is the likelihood of their children being affected by this condition?
What is the likelihood of their children being carriers without the condition?
What is the likelihood of their asymptomatic children being carriers?
Suppose that an individual with the condition has children with a heterozygous individual, what is the likelihood of their children being carriers?
Using the pedigree chart attached:
Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?
Chapter 13 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 13.1 - You want to determine whether genes a and b are...Ch. 13.2 - You have a true-breeding strain of...Ch. 13.3 - What mechanisms are responsible for: (a)...Ch. 13.4 - A man has Simpson syndrome, an addiction to a...Ch. 13.4 - Prob. 2SBCh. 13.5 - Prob. 1SBCh. 13 - In humans, redgreen color blindness is an X-linked...Ch. 13 - The following pedigree shows the pattern of...Ch. 13 - Individuals affected by a condition known as...Ch. 13 - A number of genes carried on the same chromosome...
Ch. 13 - Prob. 5TYKCh. 13 - Discuss Concepts Can a linkage map be made for a...Ch. 13 - In Drosophila, two genes, one for body color and...Ch. 13 - Another gene in Drosophila determines wing length....Ch. 13 - Prob. 9TYKCh. 13 - You conduct a cross in Drosophila that produces...Ch. 13 - Discuss Concepts Crossing-over does not occur...Ch. 13 - Prob. 12TYKCh. 13 - Prob. 13TYKCh. 13 - Prob. 14TYKCh. 13 - Prob. 1ITDCh. 13 - Prob. 2ITDCh. 13 - Prob. 3ITDCh. 13 - Prob. 4ITD
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- How does a positive ASO test for sickle-cell anemia determine that an individual is homozygous recessive for the mutation that causes sickle-cell anemia?arrow_forwardGiven the pedigree below: Is the trait dominant or recessive? What are the most likely genotypes of individuals I-1 and I-2? What is the probability that individual II-2 is a carrier?arrow_forwardIn humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A). What is the genotype of someone who has cystic fibrosis? What are the two different genotypes that a healthy person could have? If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.arrow_forward
- Tay-Sachs disease is a recessive genetic disease. Two individuals, both of whom are heterozygous for a recessive allele that causes the disease have one child who does not have the disease. What is the probability that this child has the potential to pass the disease-causing allele on to the next generation? Tay-Sachs disease is a recessive genetic disease. Two individuals, both of whom are heterozygous for a recessive allele that causes the disease have one child who does not have the disease. What is the probability that this child has the potential to pass the disease-causing allele on to the next generation? 1/4 1/2 3/4 2/3arrow_forwardAlbinism is a recessive disorder where there is a lack of melanin. Andrea and her husband Claude both have normal skin pigmentation. Andrea’s mother has the albino phenotype, but her father and her brother do not (normal pigmentation). Claude’s parents are both normal, but he has a sister who has the condition (is albino). Answer the following questions If Andrea and Claude are carriers for the albino allele, what is the probability that they have an albino child? If Andrea and Claude have a second child, what is the probability this child be normal (non-albino)? NOTE: Draw a punnet square or show your work.arrow_forwardWhich mode of inheritance is suggested by the following pedigree? Based on this hypothesis, and assuming that the trait is rare and has complete penetrance, what are the possible genotypes of all individuals in this pedigree?arrow_forward
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