Interpretation: The efficient synthesis of the conversion of compound
Concept Introduction:
The reactions of
The mechanism of acid-catalyzed ring opening of an Epoxide occurs in two steps.
In first step, the protonation of Epoxide occurs.
In second step, the attack of nucleophile occurs in the protonated Epoxide by
Under acidic condition, attack takes place at more substituted place.
Under basic condition, attack takes place at less substituted place.
PCC [Pyridinium chlorochromate]:
It is a selective oxidizing agent and it well work with secondary alcohols. Secondary alcohol reaction with PCC (oxidizing agent) provides
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