Biology
Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Chapter 13.4, Problem 1CSC
Summary Introduction

To describe: The way in which functional chloride channel (CFTR protein) can produce CFTR alleles that cause cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disorder that causes severe damage to the lungs, pancreas, digestive system, and other parts of the body. This genetic disorder affects the cells that produce sweat and mucus. In cystic fibrosis, a mutation in a gene changes a protein that controls the movement of salt in and out of cells, resulting in a thick, sticky mucus in the respiratory, reproductive and digestive system as well as increased salt in sweat.

Summary Introduction

To describe: The way in which a gene can affect the timing and rate of transcription and translation.

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Which of the following mutations would be most likely to have the most negative effect on the functioning of a protein produced by the gene? Group of answer choices a deletion of one nucleotide at the beginning of the coding sequence a substitution of one nucleotide at the beginning of the coding sequence an insertion of three nucleotides near the end of the coding sequence a substitution of one nucleotide near the end of the coding sequence
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