Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 14, Problem 3QP
Summary Introduction
To determine: The method with which established that induced pluripotent stem cells derived from the adult skin cells are really pluripotent.
Introduction: The cells that possess the ability to differentiate into several types of cells, and also the ability of self-renewal are known as stem cells. Embryonic stem cells and adult stem cells are two types of stem cells. Bone marrow and the umbilical cord blood are the two main sources to extract stem cells. Induced pluripotent stem cells are the third type of stem cells which are artificially developed in the laboratories.
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Chapter 14 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 14.6 - Suppose you are arrested for a serious crime and a...Ch. 14.6 - Prob. 2EGCh. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Can DNA profiling identify the source of a sample...Ch. 14 - Biopharming: Making Human Proteins in Animals...Ch. 14 - Prob. 2QPCh. 14 - Prob. 3QPCh. 14 - Genetically Modified Foods The creation of...Ch. 14 - Prob. 5QP
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- Stem cells: How do you think stem cells could be used to treat diseases?arrow_forwardCellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Question: A drug that has been screened in cancer model through the generation of induced pluripotent stem cells. Please explain in detail the main findings.arrow_forwardMark and label the locations of pluripotent stem cells, adult/tissue stem cells and somatic cells in the diagram to the right. What potency is the red cell on top?arrow_forward
- Which component of cell division machinery is frequently targeted by anti-cancer drugs? Can you explain the common side-effects of chemotherapy (e.g. hair loss, mucositis) based on this information?arrow_forwardSome cancer cells are insensitive to typical chemotherapy. Research into the mechanisms underlying this insensitivity uncovered an ability by these cells to pump the treatment drug out of the cell against its concentration gradient. Additional drugs have been developed that inhibit the pump, thus trapping the chemotherapeutic agent inside to promote cancer cell destruction. The Figure shows what happens when two types of cells are treated with a 3H-labeled anti-cancer drug, paclitaxel. Two additional drugs, imatinib and nilotinib, are evaluated for their ability to overcome the cancer cells ability to pump out the chemotherapeutic agent. An asterisk (*) indicates a statistically significant difference from the cells receiving paclitaxel alone. Do the additional drugs seem to the effective in over-coming the pump? Which set of graphs (A or B) best supports your answer? Explain your answer.arrow_forwardSome cancer cells are insensitive to typical chemotherapy. Research into the mechanisms underlying this insensitivity uncovered an ability by these cells to pump the treatment drug out of the cell against its concentration gradient. Additional drugs have been developed that inhibit the pump, thus trapping the chemotherapeutic agent inside to promote cancer cell destruction. The Figure shows what happens when two types of cells are treated with a 3H-labeled anti-cancer drug, paclitaxel. Which set of cells (A or B) would be described as resistant to the cancer treatment? Explain your answer. What type of transport are the resistant cells using?arrow_forward
- Excerpt from "Stem Cells Applications in Regenerative Medicine and Disease Therapeutics" by Ranjeet Mahla (2016)Regenerative medicine... deals with functional restoration of specific tissue and/or organ of the patients suffering with severe injuries or chronic disease conditions, in the state where bodies own regenerative responses do not suffice. Donated tissues and organs cannot meet the transplantation demands of aged and diseased populations that have driven the thrust for search for the alternatives. Stem cells are endorsed with indefinite cell division potential, and can [differentiate] into other types of cells. Stem cells pave foundation for all tissue and organ system of the body and mediates diverse role in disease progression, development, and tissue repair processes in host. 18) Which statement, summarized from the excerpt, best supports the claim that stem cells can be used in regenerative therapeutic technology to treat organ failure or congenital disease for a…arrow_forwardReports in the media about stem cells usually state that they “turn into any kind of cell in the body.” Explain why this statement is only partially correct, including a description of how a stem cell maintains the population of stem cells.arrow_forwardQuorum sensing is triggered to begin when ___________. a. treatment with antibiotics occurs b. bacteria release growth hormones c. bacterial protein expression is switched on d. a sufficient number of bacteria are presentarrow_forward
- Adult stem cells, such as those in the bone marrow, brain, or hair follicles, can best be described as ______, whereas embryonic stem cells are described as ______. a. totipotent; pluripotent b. pluripotent; multipotent c. multipotent; pluripotent d. totipotent; multipotentarrow_forwardDescribe and give an example of the following types of stem cells: - totipotent - pluripotentarrow_forwardMouse embryonic fibroblasts, or MEFs, are useful in stem cell culturing, as… they are sensitive to enzymatic digest. they can be grown in multilayer flasks. they provide factors that help stem cells retain their pluripotent state. they are used to check stem cell overgrowth.arrow_forward
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