The somatic cells of most individuals with Down syndrome contain an extra chromosome 21, for a total of forty-seven chromosomes. a. At which stage(s) of meiosis could nondisjunction alter the chromosome number? b. A few individuals with Down syndrome have forty-six chromosomes: two normal-appearing chromosomes 21, and a longer-than-normal chromosome 14. Speculate on how this chromosome abnormality may arise.

Human Biology (MindTap Course List)
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Chapter20: Chromosomes And Human Genetics
Section: Chapter Questions
Problem 3CT: People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes....
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The somatic cells of most individuals with Down syndrome contain an extra chromosome 21, for a total of forty-seven chromosomes.
a. At which stage(s) of meiosis could nondisjunction alter the chromosome number?
b. A few individuals with Down syndrome have forty-six chromosomes: two normal-appearing chromosomes 21, and a longer-than-normal
chromosome 14. Speculate on how this chromosome abnormality may arise.

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