Chapter 15, Problem 15.79EP

(a)

Interpretation Introduction

Interpretation: To identify the compound(s) to which leucine is metabolized.

Concept introduction: Amino acids are the main building blocks of proteins. Amino acids that participate in peptide bond synthesis in proteins are known as standard amino acids.

There are 20 standard amino acids and each amino acids have different metabolic degradation pathways for their carbon skeleton. The degradation pathways for different amino acids merge in between and result in the formation of only 7 products. The 7 products are $\text{α-ketoglutarate}$, $\text{succinyl CoA}$, fumarate, oxaloacetate, pyruvate, $\text{acetyl CoA}$ and $\text{acetoacetyl CoA}$.

(b)

Interpretation Introduction

Interpretation: To identify the compound(s) to which isoleucine is metabolized.

Concept introduction: Amino acids are the main building blocks of proteins. Amino acids that participate in peptide bond synthesis in proteins are known as standard amino acids.

There are 20 standard amino acids and each amino acids have different metabolic degradation pathways for their carbon skeleton. The degradation pathways for different amino acids merge in between and result in the formation of only 7 products. The 7 products are $\text{α-ketoglutarate}$, $\text{succinyl CoA}$, fumarate, oxaloacetate, pyruvate, $\text{acetyl CoA}$ and $\text{acetoacetyl CoA}$.

(c)

Interpretation Introduction

Interpretation: To identify the compound(s) to which aspartate is metabolized.

Concept introduction: Amino acids are the main building blocks of proteins. Amino acids that participate in peptide bond synthesis in proteins are known as standard amino acids.

There are 20 standard amino acids and each amino acids have different metabolic degradation pathways for their carbon skeleton. The degradation pathways for different amino acids merge in between and result in the formation of only 7 products. The 7 products are $\text{α-ketoglutarate}$, $\text{succinyl CoA}$, fumarate, oxaloacetate, pyruvate, $\text{acetyl CoA}$ and $\text{acetoacetyl CoA}$.

(d)

Interpretation Introduction

Interpretation: To identify the compound(s) to which arginine is metabolized.

Concept introduction: Amino acids are the main building blocks of proteins. Amino acids that participate in peptide bond synthesis in proteins are known as standard amino acids.

There are 20 standard amino acids and each amino acids have different metabolic degradation pathways for their carbon skeleton. The degradation pathways for different amino acids merge in between and result in the formation of only 7 products. The 7 products are $\text{α-ketoglutarate}$, $\text{succinyl CoA}$, fumarate, oxaloacetate, pyruvate, $\text{acetyl CoA}$ and $\text{acetoacetyl CoA}$.