Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Question
Chapter 15, Problem 1P
Summary Introduction

To examine:  Whether the statement “all second messengers are water-soluble and diffuse freely through the cytosol” is true or false.

Introduction:

Second messengers are small intracellular signaling molecules which are released in response to extracellular signals known as first messengers. They are of three types- hydrophobic, hydrophilic, and gaseous.

Expert Solution & Answer
Check Mark

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

Second messengers are classified into three types: hydrophobic, hydrophilic, and gaseous. Hydrophobic molecules are water insoluble (fat soluble) and diffuse from the plasma membrane, for example, diacyl glycerol. Hydrophilic molecules such as cyclic AMP are water soluble and diffuse in the cytosol. Gaseous molecules such as carbon monoxide can diffuse through both plasma membrane and cytosol. Thus, all second messengers are not water-soluble.

Hence, the statement is false.

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