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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 15, Problem 3QP
Textbook Problem
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Before the advent of recombinant DNA technology, why was it so difficult for geneticists to map human genes by using pedigrees? How did recombinant DNA technology help move things forward?

Summary Introduction

To determine: The difficulties faced by geneticists in mapping the human genes by using pedigrees.

Introduction: The pedigree analysis is the basic method in human genetics. It is an important tool to study human inherited diseases. The pedigree analysis is mostly used to examine the mode of the inheritance of different genetic diseases.

Explanation of Solution

The pedigree analysis is a common method in human genetics, but to study the process of linkage is difficult by using pedigrees. In the case of linkage, two genes are being analyzed and they require large multigenerational pedigrees...

Summary Introduction

To determine: The significance of recombinant DNA technology in mapping the human genes.

Introduction: Recombinant DNA technology significantly changed the gene-mapping method. Positional cloning is a recombinant DNA-based method that is used for mapping and the cloning of genes. In this method, prior information about the gene product or its function is not required.

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