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A couple who wishes to have children visits you, a genetic counselor. There is a history of a deleterious recessive trait in males in the woman’s family but not in the man’s family. The couple is convinced that because his family shows no history of this genetic disease, they are not at risk of having affected children. What steps would you take to assess this situation and educate the couple?

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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Chapter
Section
BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 16, Problem 15QP
Textbook Problem
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A couple who wishes to have children visits you, a genetic counselor. There is a history of a deleterious recessive trait in males in the woman’s family but not in the man’s family. The couple is convinced that because his family shows no history of this genetic disease, they are not at risk of having affected children. What steps would you take to assess this situation and educate the couple?

Summary Introduction

To determine: The possible steps that should be taken to assess the situation and in educating the couple.

Introduction: In the given case, the family of a woman has a history of deleterious recessive trait in males, but there is no such history in the man’s family. Even after this, the couple is convinced that there are no risks of having a genetic disease because the man’s family shows no history of the genetic disease.

Explanation of Solution

The presence of a single deleterious recessive allele in an individual makes the individual carrier for the disease. When two deleterious recessive alleles are present together, it becomes lethal and the individual dies. As a genetic counselor, the first thing that should be assessed is the genotype of the man and the family. It is because; there might be the chances that the family members are carriers of the disease.

The couple should be educated about that the chances of their child to be affected does not becomes less if only the female’s family has the disease...

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