Chapter 16, Problem 16.81P

Interpretation Introduction

Interpretation:

The given Grignard reaction has to be completed and using models it should be predicted that the predominating product enatiomer.

Concept introduction:

Alkyl or aryl magnesium halides (RMgX) are known as Grignard reagent. The Grignard reaction is an organometallic chemical reaction in which the Grignard reagent act as nucleophile and attack electrophilic carbon atom that are present within polar bonds to yield a carbon-carbon bond.

Synthesis of Grignard reagent is shown below,

$\underset{Alkyl/arylhalide}{R-X}+Mg\stackrel{Ether}{\to }\underset{Grignardreagent}{RMgX}$

The alkyl halide can be prepared from alcohol through different methods, preparing alkyl halide using thionyl chloride is one of the important methods and it is shown below,

The alkyl halide can be prepared from alcohol through different methods, preparing alkyl halide using thionyl chloride ($SOC{l}_2$) is one of the important method and it is shown below,

$R-OH\stackrel{SOC{l}_2}{\to }R-Cl+S{O}_2+HCl$

Steric energy is caused by the geometry or conformation of a molecule. This type of repulsive interaction occurs when the groups that are not directly bonded, closely approach each other. There is an increase in the energy when atoms are close to each other, as the electron densities associated with the atoms require an optimum distance of separation for the minimal interaction. This results in the steric hindrance that slows down the chemical reactions due to the presence of the steric bulk.