Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 16, Problem 16P

Consider the phylogenetic tree below with three related species (A, B, C) that share a common ancestor (last common ancestor, or LCA). The lineage leading to species A diverges before the divergence of species B and C.

For gene X, no gene duplications have occurred in any lineage, and each gene X is derived from the ancestral gene X via speciation events. Are genes AX, BX, and CX orthologous, paralogous, or homologous?

For gene Y, a gene duplication occurred in the lineage leading to A after it diverged from that leading to B and C. Are genes AY1 and AY2 orthologous or paralogous? Are genes AY1 and BY orthologous or paralogous? Are genes BY and CY orthologous or paralogous?

For gene Z, gene duplications have occurred in all species. Define orthology and paralogy relationships for the different Z genes.

Chapter 16, Problem 16P, 16.16 Consider the phylogenetic tree below with three related species (A, B, C) that share a common

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Which of the following best explains why coalescent-based phylogenetic inference is important in the age of phylogenomics?     A) Coalescent-based methods directly model gene tree histories independently to infer the species tree in a summary-based manner, which is important for phylogenomic analysis were hundreds to thousands of gene histories are analyzed.     B) Coalescent-based methods have the most advanced evolutionary models of molecular evolution, which is important for phylogenomic analysis were hundreds to thousands of gene histories are analyzed.     C) Coalescent-based methods are no more important than other types of phylogenetic inference, even for phylogenomic analyses.     D) None of the above.
Can you answer all the parts to this diagram  Species 1 and 2 are sister species from which you’ve cloned related genes. On the gene tree on the top of the next page, use labels to answer the following questions:  (a) Label the node that represents a gene duplication with “D,” (b) Label the nodes that represent speciation events with “S,”  (c) Pick a pair of genes that are paralogs and label them both “P.” (d) Pick a pair of genes that are orthologs and label them both “O.”

Chapter 16 Solutions

Genetic Analysis: An Integrated Approach (3rd Edition)

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