   Chapter 16, Problem 29PS

Chapter
Section
Textbook Problem

Epinephrine hydrochloride has pKa value of 9.53. What is the value of Ka? Where does the acid fit in table 16.2?

Interpretation Introduction

Interpretation:

Epinephrine hydrochloride has pKa value of 9.53. The value of Ka has to be determined.

Concept introduction:

Acid:

An acid is a substance that generates hydronium ions, H3O+ when added to the water.

Strong acid:

Strong acids are completely ionised in water.

For example,

HCl H2O H3O++ Cl-

Weak acid:

Weak acids are partially ionised in water.

For example,

HF + H2OH3O++ F-

pKa is define as the negative logarithm of Ka

Explanation

The Ka  of Epinephrine hydrochloride is calculated by using pKa formula.

Given:

pKa= 9.53

9.53 = -log(Ka)Ka=10-9.53=2.95×10-10

The Ka epinephrine hydrochloride is 2.95×1010

Acid fit between HCO3-

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