Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 16.1, Problem 1COMQ
Which of the following are examples of molecular changes that can have an epigenetic effect on gene expression?
a. Chromatin remodeling
b. Covalent histone modification
c. Localization of histone variants
d. DNA methylation
e. Feedback loops
f. All of the above
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Students have asked these similar questions
What are epigenetic modifications? a. the addition of reversible changes to histone proteins and DNA b. the removal of nucleosomes from the DNA c. the addition of more nucleosomes to the DNA d. mutation of the DNA sequence
Epigenetic marks regulate gene expression.
Which epigenetic mark is NOT associated with positive gene expression?
A. Histone acetylation
B. Histone Methylation
C. De-methylated DNA
D. Methylated DNA
Which of the following is an example of epigenetic modulation?
a)
Ionization-induced DNA damage
b)
Single nucleotide polymorphism (SNP)
c)
Free-radical induced DNA damage
d)
Histone modifications of DNA
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- Which of the following is not a possible outcome of changing the epigenetic code? a) exposure of regulatory region b) binding of transcription factors c) altered gene expression d) repositioning of nucleosomes by polymerasesarrow_forwardThe key to epigenetic regulation is ________. a. controlling accessibility to transcription factors and RNA polymerase binding b. biochemical modification of binding factors c. physical modification of the DNAarrow_forwardWhich of the following is NOT a description of an epigenetic modification? A. regulatory patterns that persisis in the absence of the original signal B. stable alterations in gene expression without changes to the underlying DNA sequence C. the persistence of gene expression patterns through cell division D. an intrinsic signal that triggers cell differentiationarrow_forward
- Which of the following is not a major mechanism of epigenetic change? a. DNA methylation b. Alteration of a DNA base sequence in a promoter c. Histone acetylation d. Action of RNA moleculesarrow_forwardWhich of the following could represent an epigenetic modification in a cell? A. Deletion of chromosome 18 B. Acetylation of histone H3 C. Deletion of a 20-nucleotide segment of chromosome 3 D. Conversion of an A to a T within a gene E. Duplication of chromosome 13arrow_forwardA researcher has identified a mutant strain of yeast whose histones are unable to be acetylated. Which of the following is the MOST reasonable prediction for how the phenotype of this mutant yeast will differ from the phenotype of yeast cells with acetylated histones? A. The mutant will grow more rapidly. B. The mutant will grow much more slowly. C. The mutant will show decreased levels of gene expression. D. The mutant will show increased levels of gene expression.arrow_forward
- Which of the following is an explanation for how there can be differential gene expression throughout a multicellular organism? A) There are unique sets of genes present in the different tissues of the organisms B) Some tissues have histones, while other cells do not use histones C) There are unique combinations of transcription factors in different tissues of the organism D) Different tissues throughout the organism use different genetic coding rules .arrow_forwardAccording to the histone-code hypothesis, what is one way that cell specialization occurs? a) Differential DNA methylation patterns b) Variation in enhancers in different cells c) TFII transcription factors binding to different histones in a cell-specific manner d) Differential expression of histone modifying enzymes e) Different histones are expressed in different cellsarrow_forwarda) What is a gene promoter? b) What proteins bind to a promoter? c) What do those proteins do to control gene expression?arrow_forward
- If a mutation occurred in a control element sequence associated with a particular gene, which of the following would be a likely consequence of this? A. This mutation is not likely to affect the expression of the associated gene, because RNA polymerase does not bind to control elements. B. This will likely affect the expression of the associated gene because it will loosen the coiling of chromatin at this site. C. The expression of the associated gene will be affected because this change will result in a nonsense mutation. D. This mutation is not likely to affect the expression of the associated gene, since control elements are noncoding sequences. E. The associated gene's expression would likely be affected, since this mutation would change the ability of at least one transcription factor to bind.arrow_forwardWhich of the following is true of CpG islands? a. They are methylated near promoters of actively transcribed genes. b. They are unmethylated near promoters of actively transcribed genes. c. Acetylation of CpG islands leads to repression of transcription. d. CpG islands code for RNA molecules that activate transcription.arrow_forwardList and briefly describe five types of molecular mechanisms thatmay underlie epigenetic gene regulation.arrow_forward
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