Biology: How Life Works
Biology: How Life Works
3rd Edition
ISBN: 9781319017637
Author: James Morris, Daniel Hartl, Andrew Knoll, Melissa Michael, Robert Lue, Andrew Berry, Andrew Biewener, Brian Farrell, N. Michele Holbrook
Publisher: Macmillan Higher Education
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Chapter 16.5, Problem 11SAQ
Summary Introduction

Mitochondria is a small free-floating cell organelle present throughout the eukaryotic cells. It acts as the energy storehouse that generates adenosine triphosphate (ATP) molecules. A mitochondrion is also referred to as the powerhouse of the cell due to this reason. Inherited disorders of mitochondria occur when mitochondria fail to generate enough energy molecules for the body. This dysfunctional mitochondrion leads to genetic mitochondrial diseases.

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Mitochondria generally demonstrate strictly maternal inheritance in both humans and other mammals. The organelles in the cells of offspring drive from the mother are referred to as maternal inheritance. The features of a pedigree pattern of a trait that encoded by a genome of mitochondria transferred by the maternal inheritance are given in the below figure.

Biology: How Life Works, Chapter 16.5, Problem 11SAQ

Both females and males show the maternal inheritance but, males do not transmit or inherit the trait to their offspring because offspring inherit their mitochondrial DNA from their mother only. Thus, the probability that offspring will be affected is zero in the given case.

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY