Biology (MindTap Course List)
Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 17, Problem 13TYU

CONNECT Why is an understanding of gene regulation in eukaryotes crucial to an understanding of developmental processes? Explain your answer

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It seems that developmental genetics boils down to a complex network of gene regulation. Try to draw a structure of this network for Drosophila. How many genes do you think are necessary to complete the developmental network for the fruit fly? How many genes do you think are needed for a network to specify one segment? Do you think it is more difficult to identify genes that are involved in the beginning, middle, or end of this network? Suppose you were trying to identify all of the genes needed for development in a chicken. Knowing what you know about Drosophila development, would you first try to identify genes necessary for early development, or would you begin by identifying genes involved in cell differentiation?
Think Critically. Provide a concise explanation of your answer. A mutation on an autosome causes a particular protein to be overproduced, and the excess protein accumulates in the liver and damages it. Would the resulting disorder most likely be inherited in an autosomal dominant or recessive pattern? Expression of the SYR gene on the Y chromosome gives rise to the male phenotype in humans. What do you think the inheritance pattern of SYR alleles is called? 22q11.2 deletion syndrome, also called DiGeorge syndrome, causes atypical parathyroid glands, a heart defect, and an underdeveloped thymus gland. About 85% of patients have a microdeletion of part of chromosome 22. A girl, her mother, and a maternal aunt have very mild DiGeorge syndrome. They all have a reciprocal translocation of chromosomes 22 and 2. How can a microdeletion and a translocation cause the same symptoms? Why were the people with the translocation less severely affected than the people with microdeletion? What other…
MAKE CONNECTIONS Given that changes in morphologyare often caused by changes in the regulation of geneexpression, predict whether noncoding DNA is likely to beaffected by natural selection. See Concept 18.3 to reviewnoncoding DNA and regulation of gene expression.
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY