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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 17, Problem 21QP
Textbook Problem
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Organ Transplants Must Be Immunologically

What mode of inheritance has been observed for the HLA system in humans?

Summary Introduction

To explain: The mode of inheritance that has been observed for HLA(Human Leukocyte Antigen) system in humans.

Introduction: The immune cells of the body are capable to distinguish between self and non-self cells due to the presence of MHC (major histocompatibility complex) molecules on the cells. MHC molecule has HLA genes which vary from one individual to another.

Explanation of Solution

HLA genes constitute 9 set of genes which are present inside the MHC. The HLA genes comprise of various allelic combinations which are present on the same copy of chromosome 6. A set of different genes present on the same chromosome is called a haplotype. As humans have two similar copies of a chromosome, so it is inferred that an individual has two HLA haplotypes...

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