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Organ Transplants Must Be Immunologically Matched An individual has an immunodeficiency that prevents helper T cells from recognizing the surface antigens presented by macrophages. As a result, the helper T cells are not activated, and they in turn fail to activate the appropriate B cells. At this point, is it certain that the viral infection will continue unchecked?

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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 17, Problem 31QP
Textbook Problem
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Organ Transplants Must Be Immunologically Matched

An individual has an immunodeficiency that prevents helper T cells from recognizing the surface antigens presented by macrophages. As a result, the helper T cells are not activated, and they in turn fail to activate the appropriate B cells. At this point, is it certain that the viral infection will continue unchecked?

Summary Introduction

To determine: The way in which the immune system would deal with a viral infection in case of nonactivation of T cells.

Introduction: The primary function of the immune system is to protect the body from foreign substances. Cellular immunity (T-cells and cytokines) and antibody-mediated immunity (B-cells and antibodies) are two major immunities found in an individual.

Explanation of Solution

The individual has immunodeficiency which prevents the activity of Helper T-cells. Helper T-cells would not recognize the antigens presented by macrophages. The helper T-cells cannot activate B-cells. In the absence of B-cells, antibodies would not be formed. In this condition, the body must put effort to eliminate the viral antigens...

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