menu
bartleby
search
close search
Hit Return to see all results
close solutoin list

The toxicity of many drugs is quantified by a standard called the LD 50 , the amount of drug per kilogram of body weight, required to kill 50% of the animals in a laboratory study. The LD 50 of morphine in mice is 500 mg/kg. By assuming that toxicities for humans are similar to those for mice, what would be the lethal dose of morphine for an 80-kg person?

BuyFindarrow_forward

Chemistry In Focus

7th Edition
Tro + 1 other
Publisher: Cengage Learning,
ISBN: 9781337399692

Solutions

Chapter
Section
BuyFindarrow_forward

Chemistry In Focus

7th Edition
Tro + 1 other
Publisher: Cengage Learning,
ISBN: 9781337399692
Chapter 17, Problem 68E
Textbook Problem
1 views

The toxicity of many drugs is quantified by a standard called the LD 50 , the amount of drug per kilogram of body weight, required to kill 50% of the animals in a laboratory study. The LD 50 of morphine in mice is 500 mg/kg. By assuming that toxicities for humans are similar to those for mice, what would be the lethal dose of morphine for an 80-kg person?

Interpretation Introduction

Interpretation:

The lethal dose of morphine for an 80 kg person is to be determined.

Concept Introduction:

LD50 is a standard amount of drug required per kg of the body weight.

To perform a conversion between 2 units, a quantity given in a particular unit is converted into another unit. This type of conversion is as follows:

(quantity given)×(conversion factor)=(quantity sought)

A conversion factor is a fraction in which the numerator is the unit into which the quantity is to be converted and the denominator is the unit from which it is converted.

Explanation of Solution

Given information: The toxicity of drugs is quantified by a standard called LD50, which is the amount of drug required per kilogram of the body weight, required to kill 50% of the animals in a laboratory study. The LD50 of morphine in mice is 500 mg/kg.

First, find the conversion factor. It is given that 1 kg is equal to 500 mg

Still sussing out bartleby?

Check out a sample textbook solution.

See a sample solution

The Solution to Your Study Problems

Bartleby provides explanations to thousands of textbook problems written by our experts, many with advanced degrees!

Get Started

Chapter 17 Solutions

Chemistry In Focus
Show all chapter solutions
add
Ch. 17 - Explain how antibiotics were discovered.Ch. 17 - How do penicillins and cephalosporins kill...Ch. 17 - How do tetracyclines kill bacteria?Ch. 17 - Why can antibiotics lose their effectiveness over...Ch. 17 - Explain the difference between bacteria and...Ch. 17 - What is a retrovirus?Ch. 17 - How do nucleoside/nucleotide analogs kill viruses?Ch. 17 - Explain the role of AZT in the battle against...Ch. 17 - How do protease inhibitors work? What is their...Ch. 17 - Why is the multidrug approach important in...Ch. 17 - What is a hormone?Ch. 17 - What is the role of testosterone in males?Ch. 17 - What is the role of estrogen and progesterone in...Ch. 17 - How does the birth control pill work? What are its...Ch. 17 - What is the mini pill? How is it different from...Ch. 17 - What are steroids? Give three examples of steroids...Ch. 17 - What do cortisone and prednisone do? What are the...Ch. 17 - What do the anabolic steroids do? What are the...Ch. 17 - What is the difference between cancerous cells and...Ch. 17 - What are the side effects of chemotherapy?Ch. 17 - How do cancer-fighting chemicals target cancerous...Ch. 17 - Explain how each of the following cancer drugs...Ch. 17 - What is a depressant? What are the effects of...Ch. 17 - Where and how fast is ethanol metabolized?Ch. 17 - What are the risks associated with heavy drinking?Ch. 17 - What are the symptoms of alcoholism?Ch. 17 - How do barbiturates and benzodiazepines work? Give...Ch. 17 - List some common depressant inhalants used for...Ch. 17 - What are the dangers associated with...Ch. 17 - What are the side effects of inhaling the vapors...Ch. 17 - What is a narcotic? Give some examples.Ch. 17 - How do narcotics work?Ch. 17 - Where does morphine come from, and what are its...Ch. 17 - What are the effects of codeine and heroin? How do...Ch. 17 - What are agonists and antagonists?Ch. 17 - How do drugs like naltrexone and methadone help a...Ch. 17 - What are endorphins?Ch. 17 - What is a stimulant? Give some examples.Ch. 17 - What are the effects of cocaine and amphetamine?...Ch. 17 - How does caffeine produce its stimulant effect?Ch. 17 - What are the side effects of caffeine?Ch. 17 - How does nicotine produce its stimulant effect?Ch. 17 - What are the side effects of smoking?Ch. 17 - What is a hallucinogen? Give some examples.Ch. 17 - How do hallucinogens produce their...Ch. 17 - Who discovered LSD? How?Ch. 17 - What are the primary effects of LSD and of...Ch. 17 - What are the side effects of LSD?Ch. 17 - What is the active ingredient in marijuana?Ch. 17 - What are the primary effects of marijuana? What...Ch. 17 - What qualifies a depressed state as one requiring...Ch. 17 - How do Prozac and Zoloft produce their...Ch. 17 - Draw the chemical structure of aspirin, and...Ch. 17 - Draw the chemical structure of ibuprofen, and...Ch. 17 - Childrens Tylenol is a solution containing 32...Ch. 17 - Childrens ibuprofen is a solution containing 20...Ch. 17 - A childs dose of the antibiotic Amoxicillin is 25...Ch. 17 - A childs dose of the antibiotic Azithromycin is 25...Ch. 17 - The toxicity of many drugs is quantified by a...Ch. 17 - The LD50 (see problem 68) of cocaine in rats is...Ch. 17 - The growth in our knowledge of the chemical origin...Ch. 17 - Our senses produce a chemically mediated signal...Ch. 17 - A continuing debate in our society is over the...Ch. 17 - Although our society has condoned the recreational...Ch. 17 - A controversial book called Listening to Prozac...Ch. 17 - The life expectancy in the United States has risen...Ch. 17 - The cost of health care in the United States...Ch. 17 - Write down the last five prescription or over-the-...Ch. 17 - Survey 30 classmates, asking them to recall the...

Additional Science Textbook Solutions

Find more solutions based on key concepts
Show solutions add
Hypoglycemia as a disease is relatively common. T F

Nutrition: Concepts and Controversies - Standalone book (MindTap Course List)

What is a life cycle?

Biology: The Dynamic Science (MindTap Course List)

Earth did not rotate, could you define the celestial poles and celestial equator?

Horizons: Exploring the Universe (MindTap Course List)

Label the hearts main parts in the diagram below.

Human Biology (MindTap Course List)

Newspaper articles often contain statements such as 10 000 volts of electricity singed through the victims body...

Physics for Scientists and Engineers, Technology Update (No access codes included)

How is waters density affected by freezing? Why does ice float?

Oceanography: An Invitation To Marine Science, Loose-leaf Versin