Phosphate ions are abundant in cells, both as the ions themselves and as important substituents on organic molecules. Most importantly, the p K a for the H 2 PO 4 − ion is 7.20, which is very close to the normal pH in the body. H 2 PO 4 − (aq) + H 2 O( ℓ ) ⇄ H 3 O + (aq) + HPO 4 2− (aq) 1. What should the ratio [HPO 4 2− ]/[H 2 PO 4 − ] be to control the pH at 7.40?

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