Chapter 18, Problem 1P

Interpretation Introduction

Interpretation:

The additional substrates, product and coenzyme for the given reaction in the given imaginary pathways should be identified.

Concept Introduction:

Substrates is the molecules or substances where the enzyme acts in a chemical reaction. These chemical reactions containing the substrates catalyze the enzymes.

Molecules which help the enzyme to catalyze in a chemical reaction are called coenzymes.

Product is the molecule or the substance formed during the chemical reaction.

Explanation of Solution

In the given imaginary pathway, the following steps are followed to identify substrates products and coenzymes.

Step 1: The chemical reaction starts with isomerisation where the alignement of molecules change being the same molecule. Here, it is achieved by 5-deoxyadenosyl-B12.

Step 2: Tetrahydrofolate is used to detach aldehyde group in the molecule.

Step 3: The glutamine alone with ATP coverts the carboxylic acid to amide functional group.

Step 4: a ketoglutarate and pyridoxal phosphate is needed to convert amino group to oxygen.

Step 5: With the use of S-adenosylmethionine, the amino group is converted to primary amine.

Thus, the substrates, products and coenzymes are identified by following a few steps in the chemical reaction.