Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Textbook Question
Chapter 18, Problem 6P
The Reactions and Meehanisms of the Leloir Pathway Write the reactions that permit galactose to be utilized in glycolysis. Write a suitable mechanism, tor one of these reactions.
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Chapter 18 Solutions
Biochemistry
Ch. 18 - Characterizing Glycolysis List the reactions of...Ch. 18 - Radiotracer Labeling of Pyruvate from Glucose...Ch. 18 - Effects of Changing Metabolite Concentrations on...Ch. 18 - Prob. 4PCh. 18 - Prob. 5PCh. 18 - The Reactions and Meehanisms of the Leloir Pathway...Ch. 18 - The Effect of lodoacetic Acid on the...Ch. 18 - Prob. 8PCh. 18 - Comparing Glycolysis Entry Points for Sucrose...Ch. 18 - Prob. 10P
Ch. 18 - Prob. 11PCh. 18 - Prob. 12PCh. 18 - Prob. 13PCh. 18 - Energetic of Fructose-1 ,6-bis P Hydrolysis...Ch. 18 - Prob. 15PCh. 18 - Energetics of the Hexokinase Reaction The...Ch. 18 - Prob. 17PCh. 18 - Distinguishing the Mechanisms of Class I and Class...Ch. 18 - Prob. 19PCh. 18 - Understanding the Mechanism of Hemolytic Anemia...Ch. 18 - Prob. 21PCh. 18 - Based on your residing of this chapter, what would...Ch. 18 - Examine the ActiveModel for alcohol dehydrogenase...Ch. 18 - Based on your knowledge of the structure of NAD+...Ch. 18 - Using the ActiveModel for phosphofructokinase...
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- Extending the Mechanism of Methylmalonyl-CoA Mutase to Similar Reactions Based on the mechanism for the methylmalonyl-CoA mutase (see problem 14), write reasonable mechanisms for the following reactions shown.arrow_forwardExamine the ActiveModel for alcohol dehydrogenase and describe the structure and function of the catalytic zinc center.arrow_forwardUsing the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved residues in slightly different positions can change the catalytic rate of reaction.arrow_forward
- Write a balanced equation for the conversion of glycerol into pyruvate. Which enzymes are required in addition to those of the glycolytic pathway?arrow_forwardUsing the Krebs cycle explain oxidative decarboxylation.arrow_forwardExplain how the conversion of alanine to pyruvic acid (pyruvate) can be identified as an oxidation reaction.arrow_forward
- Enolase catalyzes the reversible reaction shown below. Draw the detailed mechanism for the reaction that occurs in gluconeogenesis, namely the reaction of phosphoenolpyruvate to form 2-phosphoglycerate (the reverse direction in the reaction below).arrow_forwardWhat if the phosphate group for the glycolysis reaction with enzyme glyceraldehyde 3-phosphate dehydrogenase was from ATP instead of Pi? What would the complete, balanced, net rxn of glycoslysisequation be and how does this impact the overall glycolysis rxn?arrow_forwardDraw the Fischer projection of galactcose and show its catabolism until it releases carbon dioxide via complete oxidation. Use inter-related reactions or pathways, correct names and number of moles of intermediates involved, and the enzymes catalyzing the reactions. Account for all the 6 carbons of thr monosaccharide as they become carbon dioxide by encircling them all throughout the pathway you have writtearrow_forward
- hexokinase catalyzes the first reaction of the glycolysis pathway. What may happen if there is xylose in the reaction place? Briefly explain.arrow_forwardDraw the Fischer projection of glucose and show its catabolism until it releases carbon dioxide via complete oxidation. Use inter-related reactions or pathways, correct names and number of moles of intermediates involved, and the enzymes catalyzing the reactions. Account for all the 6 carbons of thr monosaccharide as they become carbon dioxide by encircling them all throughout the pathway you have written.arrow_forwardGalactose can enter the glycolytic cycle but it must first react with ATP to form galactose-1-phosphate. Propose a mechanism for this reaction. OOOPO− −OOPO−O O−OPO−O OPO− OH AdO+ OOPO−arrow_forward
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