Concept explainers
To determine: The type of mutation which causes Huntington disease.
Introduction: Accumulation of misfolded proteins in the brain can lead to brain cell death and can cause several neurodegenerative disorders. Huntington disease (HD) is a neurodegenerative disorder which is inherited as an autosomal dominant trait. Cognition inability, emotional problems, and uncontrolled movements are the symptoms of HD.
To determine: The result of this mutation that results in neurodegeneration.
Introduction: Accumulation of misfolded proteins in the brain can lead to brain cell death and can cause several neurodegenerative disorders. Huntington disease (HD) is a neurodegenerative disorder which is inherited as an autosomal dominant trait. Cognition inability, emotional problems, and uncontrolled movements are the symptoms of HD.
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Human Heredity: Principles and Issues (MindTap Course List)
- Explain the a gain-of-function mutation ?arrow_forwardA region on chromosome 6 has been linked to schizophrenia, but researchers have not found a specific gene associated with this disease. What steps would be necessary to locate the gene?arrow_forwardExplain the cause of Huntington disease ? Explain its medication ?arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning