Introduction to General, Organic and Biochemistry
Introduction to General, Organic and Biochemistry
11th Edition
ISBN: 9781285869759
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
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Chapter 19, Problem 19.44P
Interpretation Introduction

(a)

Interpretation:

The name of functional group in each anesthetic should be determined.

Concept Introduction:

Lidocaine, is also recognized as lignocaine and xylocaine. This medicine is utilized to numb the tissues in a precise area. It us also utilized for the treatment of ventricular tachycardia as well as to block the nerves.

Etidocaine is recognized as local anesthetic having long action and rapid onset. It is same as BUPIVACAINE. Etidocaine is sold in the market with a name as Duranest. It is a local anesthetic provided through injection in delivery, labor and surgical processes.

Mepivacaine is a numbing medicine or anesthetic which is used to block the impulse of nerve that conveys the signal of pain into the brain. It is utilized as the local anesthetic in only single area for spinal block and epidural. It is also utilized in dental processes as a local anesthetic.

Interpretation Introduction

(b)

Interpretation:

The chiral anesthetics should be identified.

Concept Introduction:

Lidocaine is also recognized as lignocaine and xylocaine. This medicine is utilized to numb the tissues in a precise area. It us also utilized for the treatment of ventricular tachycardia as well as to block the nerves.

Etidocaine is recognized as local anesthetic having long action and rapid onset. It is same as BUPIVACAINE. Etidocaine is sold in the market with a name as Duranest. It is a local anesthetic provided through injection in delivery, labor and surgical processes.

Mepivacaine is a numbing medicine or anesthetic which is used to block the impulse of nerve that conveys the signal of pain into the brain. It is utilized as the local anesthetic in only single area for spinal block and epidural. It is also utilized in dental processes as a local anesthetic.

Interpretation Introduction

(c)

Interpretation:

The more basic nitrogen should be identified.

Concept Introduction:

Lidocaine is also recognized as lignocaine and xylocaine. This medicine is utilized to numb the tissues in a precise area. It us also utilized for the treatment of ventricular tachycardia as well as to block the nerves.

Etidocaine is recognized as local anesthetic having long action and rapid onset. It is same as BUPIVACAINE. Etidocaine is sold in the market with a name as Duranest. It is a local anesthetic provided through injection in delivery, labor and surgical processes.

Mepivacaine is a numbing medicine or anesthetic which is used to block the impulse of nerve that conveys the signal of pain into the brain. It is utilized as the local anesthetic in only single area for spinal block and epidural. It is also utilized in dental processes as a local anesthetic.

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A diuretic is a compound that causes increased urination and thereby reduces fluid volume in the body. An important use of diuretics in clinical medicine is in the reduction of the fluid buildup, particularly in the lungs, that is associated with congestive heart failure. It is also used as an antihypertensive (i.e., to reduce blood pressure). Furosemide, an exceptionally potent diuretic, is prescribed under 30 or more trade names, the best known of which is Lasix. The synthesis of furosemide begins with treatment of 2,4-dichlorobenzoic acid with chlorosulfonic acid in a reaction called chlorosulfonation. The product of this reaction is then treated with ammonia followed by heating with furfurylamine. Q. Propose a mechanism for the chlorosulfonation reaction in Step (1).
A diuretic is a compound that causes increased urination and thereby reduces fluid volume in the body. An important use of diuretics in clinical medicine is in the reduction of the fluid buildup, particularly in the lungs, that is associated with congestive heart failure. It is also used as an antihypertensive (i.e., to reduce blood pressure). Furosemide, an exceptionally potent diuretic, is prescribed under 30 or more trade names, the best known of which is Lasix. The synthesis of furosemide begins with treatment of 2,4-dichlorobenzoic acid with chlorosulfonic acid in a reaction called chlorosulfonation. The product of this reaction is then treated with ammonia followed by heating with furfurylamine. Q. Propose a mechanism for Step (3).
A diuretic is a compound that causes increased urination and thereby reduces fluid volume in the body. An important use of diuretics in clinical medicine is in the reduction of the fluid buildup, particularly in the lungs, that is associated with congestive heart failure. It is also used as an antihypertensive (i.e., to reduce blood pressure). Furosemide, an exceptionally potent diuretic, is prescribed under 30 or more trade names, the best known of which is Lasix. The synthesis of furosemide begins with treatment of 2,4-dichlorobenzoic acid with chlorosulfonic acid in a reaction called chlorosulfonation. The product of this reaction is then treated with ammonia followed by heating with furfurylamine. Q. Is furosemide chiral? If so, which of the possible stereoisomers are formed in this synthesis?
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