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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 19, Problem 2CS
Textbook Problem
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If allele frequencies in the hemoglobin gene are influenced by sickle cell anemia on the one hand and by resistance to malaria on the other hand, what factors may cause a change in these allele frequencies over time?

Summary Introduction

To determine: The factors that may cause changes in allele frequencies if the allele frequencies in the hemoglobin gene are influenced by sickle cell anemia as well by resistance to malaria.

Introduction: The allele frequency refers to number of times an allele occurs at a specific locus within a population. It can be represented as percentage or in fraction. The allele frequency is indicative of variation at a particular locus.

Explanation of Solution

When a population is infected by a disease then it results in the alteration of the allele frequency of that population. In the case of malaria, if the proportion of the population affected by malaria is reduced, then it will also contribute to an decrease in sickle cell anemia. This decrease in sickle cell anemia is due to the fact that the individuals that are non carriers of this disease will be healthy and will continue to reproduce at a higher rate...

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