Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
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Chapter 19, Problem 6RE
Interpretation Introduction
Interpretation:
The steps through which pyruvate from glycolysis is converted into pyruvate dehydrogenase complex are to be explained.
Concept introduction:
The breakdown of a glucose molecule to produce ATP, NADH, and pyruvate molecules is called glycolysis.
The pyruvate is the initial reacting substrate for the citric acid cycle that goes through several reactions in the presence of the enzyme pyruvate dehydrogenase complex to give acetyl-CoA.
The pyruvate dehydrogenase complex is a set of five enzymes, namely, pyruvate dehydrogenase, hydro lipoyl transacetylase, dihydrolipoyl dehydrogenase, pyruvate dehydrogenase kinase, and pyruvate dehydrogenase phosphatase.
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Chapter 19 Solutions
Biochemistry
Ch. 19 - RECALL Which pathways are involved in the...Ch. 19 - RECALL How many ATPs can be produced from one...Ch. 19 - RECALL What are the different names used to...Ch. 19 - Prob. 4RECh. 19 - Prob. 5RECh. 19 - Prob. 6RECh. 19 - Prob. 7RECh. 19 - RECALL What three molecules produced during the...Ch. 19 - RECALL How many enzymes are involved in mammalian...Ch. 19 - RECALL Briefly describe the dual role of lipoic...
Ch. 19 - Prob. 11RECh. 19 - Prob. 12RECh. 19 - Prob. 13RECh. 19 - Prob. 14RECh. 19 - RECALL Why is the reaction catalyzed by citrate...Ch. 19 - RECALL What does it mean when an enzyme has the...Ch. 19 - Prob. 17RECh. 19 - RECALL With respect to stereochemistry, what is...Ch. 19 - Prob. 19RECh. 19 - Prob. 20RECh. 19 - Prob. 21RECh. 19 - RECALL What are the similarities and differences...Ch. 19 - Prob. 23RECh. 19 - Prob. 24RECh. 19 - Prob. 25RECh. 19 - RECALL Why can we say that production of a GTP is...Ch. 19 - Prob. 27RECh. 19 - RECALL ATP is a competitive inhibitor of NADH...Ch. 19 - RECALL Is the conversion of fumarate to malate a...Ch. 19 - REFLECT AND APPLY We have seen one of the four...Ch. 19 - Prob. 31RECh. 19 - Prob. 32RECh. 19 - Prob. 33RECh. 19 - Prob. 34RECh. 19 - REFLECT AND APPLY How does an increase in the...Ch. 19 - REFLECT AND APPLY How does an increase in the...Ch. 19 - Prob. 37RECh. 19 - Prob. 38RECh. 19 - Prob. 39RECh. 19 - Prob. 40RECh. 19 - REFLECT AND APPLY How could the expression milking...Ch. 19 - Prob. 42RECh. 19 - Prob. 43RECh. 19 - Prob. 44RECh. 19 - BIOCHEMICAL CONNECTIONS Why is it possible for...Ch. 19 - RECALL Describe the various purposes of the citric...Ch. 19 - REFLECT AND APPLY The intermediates of glycolysis...Ch. 19 - Prob. 48RECh. 19 - REFLECT AND APPLY Many soft drinks contain citric...Ch. 19 - RECALL NADH is an important coenzyme in catabolic...Ch. 19 - BIOCHEMICAL CONNECTIONS What are the anaplerotic...Ch. 19 - REFLECT AND APPLY Why is acetyl-CoA considered the...Ch. 19 - Prob. 53RE
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- REFLECT AND APPLY Explain how the pentose phosphate path- way can respond to a cells need for ATP, NADPH, and ribose-5- phosphate.arrow_forwardRECALL What are the possible metabolic fates of pyruvate?arrow_forwardRECALL Outline the role of carnitine in the transport of acyl-CoA molecules into the mitochondrion. How many enzymes are involved? What are they called?arrow_forward
- RECALL Briefly describe the dual role of lipoic acid in the pyruvate dehydrogenase complex.arrow_forwardREFLECT AND APPLY How does the hydrolysis of fructose-1,6-bisphosphate bring about the reversal of one of the physiologically irreversible steps of glycolysis?arrow_forwardREFLECT AND APPLY How does an increase in the ADP/ATP ratio affect the activity of isocitrate dehydrogenase?arrow_forward
- REFLECT AND APPLY Why is acetyl-CoA considered the central molecule of metabolism?arrow_forwardRECALL Outline the steps involved in the production of malonyl-CoA from acetyl-CoA.arrow_forwardREFLECT AND APPLY The intermediates of glycolysis are phosphorylated, but those of the citric acid cycle are not. Suggest a reason why.arrow_forward
- RECALL What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase and -ketoglutarate dehydrogenase?arrow_forwardREFLECT AND APPLLY Show how the estimate of 33% efficiency of energy use in anaerobic glycolysis is derived.arrow_forwardREFLECT AND APPLY Why does the degradation of palmitic acid (see Question 12) to eight molecules of acetyl-CoA require seven, rather than eight, rounds of the -oxidation process?arrow_forward
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